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Effects of Glucagon-like Peptide-1 on the Reproductive Axis in Healthy Men.
Izzi-Engbeaya C, Jones S, Crustna Y, Machenahalli PC, Papadopoulou D, Modi M, Panayi C, Starikova J, Eng PC, Phylactou M, Mills E, Yang L, Ratnasabapathy R, Sykes M, Plumptre I, Coumbe B, Wing VC, Pacuszka E, Bech P, Minnion J, Tharakan G, Tan T, Veldhuis J, Abbara A, Comninos AN, Dhillo WS. Izzi-Engbeaya C, et al. Among authors: dhillo ws. J Clin Endocrinol Metab. 2020 Apr 1;105(4):1119-25. doi: 10.1210/clinem/dgaa072. J Clin Endocrinol Metab. 2020. PMID: 32052032 Free PMC article. Clinical Trial.
Ghrelin enhances appetite and increases food intake in humans.
Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR. Wren AM, et al. Among authors: dhillo ws. J Clin Endocrinol Metab. 2001 Dec;86(12):5992. doi: 10.1210/jcem.86.12.8111. J Clin Endocrinol Metab. 2001. PMID: 11739476 Free article. Clinical Trial.
Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males.
Dhillo WS, Chaudhri OB, Patterson M, Thompson EL, Murphy KG, Badman MK, McGowan BM, Amber V, Patel S, Ghatei MA, Bloom SR. Dhillo WS, et al. J Clin Endocrinol Metab. 2005 Dec;90(12):6609-15. doi: 10.1210/jc.2005-1468. Epub 2005 Sep 20. J Clin Endocrinol Metab. 2005. PMID: 16174713 Clinical Trial.
Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis.
Jayasena CN, Nijher GM, Chaudhri OB, Murphy KG, Ranger A, Lim A, Patel D, Mehta A, Todd C, Ramachandran R, Salem V, Stamp GW, Donaldson M, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: dhillo ws. J Clin Endocrinol Metab. 2009 Nov;94(11):4315-23. doi: 10.1210/jc.2009-0406. Epub 2009 Oct 9. J Clin Endocrinol Metab. 2009. PMID: 19820030 Clinical Trial.
Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea.
Jayasena CN, Nijher GM, Abbara A, Murphy KG, Lim A, Patel D, Mehta A, Todd C, Donaldson M, Trew GH, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: dhillo ws. Clin Pharmacol Ther. 2010 Dec;88(6):840-7. doi: 10.1038/clpt.2010.204. Epub 2010 Oct 27. Clin Pharmacol Ther. 2010. PMID: 20980998 Clinical Trial.
294 results