Chen X - Search Results

1

A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α.

Wang X, Chen X, Zhang X, Su C, Yang M, He W, Du Y, Si S, Wang L, Hong B. Wang X, et al. Among authors: chen x. EBioMedicine. 2020 Feb;52:102650. doi: 10.1016/j.ebiom.2020.102650. Epub 2020 Feb 12. EBioMedicine. 2020. PMID: 32058941 Free PMC article.

2

Discovery of antagonists for human scavenger receptor CD36 via an ELISA-like high-throughput screening assay.

Wang L, Bao Y, Yang Y, Wu Y, Chen X, Si S, Hong B. Wang L, et al. Among authors: chen x. J Biomol Screen. 2010 Mar;15(3):239-50. doi: 10.1177/1087057109359686. Epub 2010 Feb 11. J Biomol Screen. 2010. PMID: 20150587

3

Design, synthesis and biological evaluation of hydroxamic acid derivatives as potential high density lipoprotein (HDL) receptor CLA-1 up-regulating agents.

Chen X, Wang L, Du Y, Wu Y, Jia X, Yang Y, Hong B. Chen X, et al. Molecules. 2011 Nov 2;16(11):9178-93. doi: 10.3390/molecules16119178. Molecules. 2011. PMID: 22048700 Free PMC article.

4

Structure-activity relationship and biological evaluation of xanthine derivatives as PCSK9 inhibitors for the treatment of atherosclerosis.

Qiao MQ, Li Y, Yang YX, Pang CX, Liu YT, Bian C, Wang L, Chen XF, Hong B. Qiao MQ, et al. Eur J Med Chem. 2023 Feb 5;247:115047. doi: 10.1016/j.ejmech.2022.115047. Epub 2022 Dec 26. Eur J Med Chem. 2023. PMID: 36586297

5

Synthesis and structure-activity relationships of novel 14-membered 2-fluoro ketolides with structural modification at the C11 position.

Bian C, Zhang J, Zheng X, Qiao M, Li Y, Chen X, Si S. Bian C, et al. Among authors: chen x. Eur J Med Chem. 2024 Mar 5;267:116181. doi: 10.1016/j.ejmech.2024.116181. Epub 2024 Feb 3. Eur J Med Chem. 2024. PMID: 38354519

6

Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.

Sun L, Wang C, Hu X, Wu Y, Jiang Z, Li Z, Chen X, Hu L. Sun L, et al. Among authors: chen x. Bioorg Chem. 2020 Jun;99:103766. doi: 10.1016/j.bioorg.2020.103766. Epub 2020 Mar 19. Bioorg Chem. 2020. PMID: 32247110

7

Novel carbazole sulfonamide derivatives of antitumor agent: Synthesis, antiproliferative activity and aqueous solubility.

Sun L, Wu Y, Liu Y, Chen X, Hu L. Sun L, et al. Among authors: chen x. Bioorg Med Chem Lett. 2017 Jan 15;27(2):261-265. doi: 10.1016/j.bmcl.2016.11.068. Epub 2016 Nov 25. Bioorg Med Chem Lett. 2017. PMID: 27919655

8

Synthesis and structure-activity relationship of novel bisindole amidines active against MDR Gram-positive and Gram-negative bacteria.

Liu Y, Hu X, Wu Y, Zhang W, Chen X, You X, Hu L. Liu Y, et al. Among authors: chen x. Eur J Med Chem. 2018 Apr 25;150:771-782. doi: 10.1016/j.ejmech.2018.03.031. Epub 2018 Mar 12. Eur J Med Chem. 2018. PMID: 29604581

9

Synthesis and in vitro activity of dicationic indolyl diphenyl ethers as novel potent antibiotic agents against drug-resistant bacteria.

Chen X, Hu X, Wu Y, Liu Y, Bian C, Nie T, You X, Hu L. Chen X, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):841-844. doi: 10.1016/j.bmcl.2017.01.019. Epub 2017 Jan 10. Bioorg Med Chem Lett. 2017. PMID: 28109787

10

[Design, synthesis of quinolinone acid-containing compounds with anti-HIV integrase activity].

Chen XF, Wu YB, Jin J, Wang RZ, Wang C, Liu J. Chen XF, et al. Yao Xue Xue Bao. 2010 Feb;45(2):263-7. Yao Xue Xue Bao. 2010. PMID: 21351438 Chinese.

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