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Effect of Intravenous Interferon β-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.
Ranieri VM, Pettilä V, Karvonen MK, Jalkanen J, Nightingale P, Brealey D, Mancebo J, Ferrer R, Mercat A, Patroniti N, Quintel M, Vincent JL, Okkonen M, Meziani F, Bellani G, MacCallum N, Creteur J, Kluge S, Artigas-Raventos A, Maksimow M, Piippo I, Elima K, Jalkanen S, Jalkanen M, Bellingan G; INTEREST Study Group. Ranieri VM, et al. Among authors: bellingan g. JAMA. 2020 Feb 25;323(8):725-733. doi: 10.1001/jama.2019.22525. JAMA. 2020. PMID: 32065831 Clinical Trial.
High-frequency oscillation for acute respiratory distress syndrome.
Young D, Lamb SE, Shah S, MacKenzie I, Tunnicliffe W, Lall R, Rowan K, Cuthbertson BH; OSCAR Study Group. Young D, et al. N Engl J Med. 2013 Feb 28;368(9):806-13. doi: 10.1056/NEJMoa1215716. Epub 2013 Jan 22. N Engl J Med. 2013. PMID: 23339638 Free article. Clinical Trial.
The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study.
Bellingan G, Maksimow M, Howell DC, Stotz M, Beale R, Beatty M, Walsh T, Binning A, Davidson A, Kuper M, Shah S, Cooper J, Waris M, Yegutkin GG, Jalkanen J, Salmi M, Piippo I, Jalkanen M, Montgomery H, Jalkanen S. Bellingan G, et al. Lancet Respir Med. 2014 Feb;2(2):98-107. doi: 10.1016/S2213-2600(13)70259-5. Epub 2013 Dec 23. Lancet Respir Med. 2014. PMID: 24503265 Clinical Trial.
Simvastatin in the acute respiratory distress syndrome.
McAuley DF, Laffey JG, O'Kane CM, Perkins GD, Mullan B, Trinder TJ, Johnston P, Hopkins PA, Johnston AJ, McDowell C, McNally C; HARP-2 Investigators; Irish Critical Care Trials Group. McAuley DF, et al. N Engl J Med. 2014 Oct 30;371(18):1695-703. doi: 10.1056/NEJMoa1403285. Epub 2014 Sep 30. N Engl J Med. 2014. PMID: 25268516 Free article. Clinical Trial.
Comparison of the efficacy and safety of FP-1201-lyo (intravenously administered recombinant human interferon beta-1a) and placebo in the treatment of patients with moderate or severe acute respiratory distress syndrome: study protocol for a randomized controlled trial.
Bellingan G, Brealey D, Mancebo J, Mercat A, Patroniti N, Pettilä V, Quintel M, Vincent JL, Maksimow M, Jalkanen M, Piippo I, Ranieri VM. Bellingan G, et al. Trials. 2017 Nov 13;18(1):536. doi: 10.1186/s13063-017-2234-7. Trials. 2017. PMID: 29132404 Free PMC article. Clinical Trial.
Intravenous Interferon β-1a for Severe ARDS-Reply.
Bellingan G, Ranieri VM, Karvonen MK. Bellingan G, et al. JAMA. 2020 Aug 4;324(5):515-516. doi: 10.1001/jama.2020.7992. JAMA. 2020. PMID: 32749487 No abstract available.
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