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CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, Wolchok JD, Merghoub T, Jandus C, Zippelius A, Ho PC. Wang H, et al. Among authors: jandus c. Nat Immunol. 2020 Mar;21(3):298-308. doi: 10.1038/s41590-019-0589-5. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066953 Free PMC article.
Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment.
Haas Q, Boligan KF, Jandus C, Schneider C, Simillion C, Stanczak MA, Haubitz M, Seyed Jafari SM, Zippelius A, Baerlocher GM, Läubli H, Hunger RE, Romero P, Simon HU, von Gunten S. Haas Q, et al. Among authors: jandus c. Cancer Immunol Res. 2019 May;7(5):707-718. doi: 10.1158/2326-6066.CIR-18-0505. Epub 2019 Apr 15. Cancer Immunol Res. 2019. PMID: 30988027
The pro- and anti-tumor role of ILC2s.
Trabanelli S, Chevalier MF, Derré L, Jandus C. Trabanelli S, et al. Among authors: jandus c. Semin Immunol. 2019 Feb;41:101276. doi: 10.1016/j.smim.2019.04.004. Epub 2019 May 23. Semin Immunol. 2019. PMID: 31130471 Review.
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells.
Mastelic-Gavillet B, Navarro Rodrigo B, Décombaz L, Wang H, Ercolano G, Ahmed R, Lozano LE, Ianaro A, Derré L, Valerio M, Tawadros T, Jichlinski P, Nguyen-Ngoc T, Speiser DE, Verdeil G, Gestermann N, Dormond O, Kandalaft L, Coukos G, Jandus C, Ménétrier-Caux C, Caux C, Ho PC, Romero P, Harari A, Vigano S. Mastelic-Gavillet B, et al. Among authors: jandus c. J Immunother Cancer. 2019 Oct 10;7(1):257. doi: 10.1186/s40425-019-0719-5. J Immunother Cancer. 2019. PMID: 31601268 Free PMC article.
ILC2s: New Actors in Tumor Immunity.
Ercolano G, Falquet M, Vanoni G, Trabanelli S, Jandus C. Ercolano G, et al. Among authors: jandus c. Front Immunol. 2019 Dec 3;10:2801. doi: 10.3389/fimmu.2019.02801. eCollection 2019. Front Immunol. 2019. PMID: 31849977 Free PMC article. Review.
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
Yu YR, Imrichova H, Wang H, Chao T, Xiao Z, Gao M, Rincon-Restrepo M, Franco F, Genolet R, Cheng WC, Jandus C, Coukos G, Jiang YF, Locasale JW, Zippelius A, Liu PS, Tang L, Bock C, Vannini N, Ho PC. Yu YR, et al. Among authors: jandus c. Nat Immunol. 2020 Dec;21(12):1540-1551. doi: 10.1038/s41590-020-0793-3. Epub 2020 Oct 5. Nat Immunol. 2020. PMID: 33020660
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Ercolano G, Gomez-Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, Michalik L, Loyon R, Ianaro A, Ho PC, Borg C, Kopf M, Merkler D, Krebs P, Romero P, Trabanelli S, Jandus C. Ercolano G, et al. Among authors: jandus c. Nat Commun. 2021 May 5;12(1):2538. doi: 10.1038/s41467-021-22764-2. Nat Commun. 2021. PMID: 33953160 Free PMC article.
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy.
Wang C, Zeng Q, Gül ZM, Wang S, Pick R, Cheng P, Bill R, Wu Y, Naulaerts S, Barnoud C, Hsueh PC, Moller SH, Cenerenti M, Sun M, Su Z, Jemelin S, Petrenko V, Dibner C, Hugues S, Jandus C, Li Z, Michielin O, Ho PC, Garg AD, Simonetta F, Pittet MJ, Scheiermann C. Wang C, et al. Among authors: jandus c. Cell. 2024 May 23;187(11):2690-2702.e17. doi: 10.1016/j.cell.2024.04.015. Epub 2024 May 8. Cell. 2024. PMID: 38723627 Free article.
89 results