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CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants.
Spisák S, Lawrenson K, Fu Y, Csabai I, Cottman RT, Seo JH, Haiman C, Han Y, Lenci R, Li Q, Tisza V, Szállási Z, Herbert ZT, Chabot M, Pomerantz M, Solymosi N; GAME-ON/ELLIPSE Consortium; Gayther SA, Joung JK, Freedman ML. Spisák S, et al. Among authors: tisza v. Nat Med. 2015 Nov;21(11):1357-63. doi: 10.1038/nm.3975. Epub 2015 Sep 23. Nat Med. 2015. PMID: 26398868 Free PMC article.
A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer.
Takeda DY, Spisák S, Seo JH, Bell C, O'Connor E, Korthauer K, Ribli D, Csabai I, Solymosi N, Szállási Z, Stillman DR, Cejas P, Qiu X, Long HW, Tisza V, Nuzzo PV, Rohanizadegan M, Pomerantz MM, Hahn WC, Freedman ML. Takeda DY, et al. Among authors: tisza v. Cell. 2018 Jul 12;174(2):422-432.e13. doi: 10.1016/j.cell.2018.05.037. Epub 2018 Jun 14. Cell. 2018. PMID: 29909987 Free PMC article.
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.
Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Börcsök J, et al. Among authors: tisza v. Clin Cancer Res. 2021 Apr 1;27(7):2011-2022. doi: 10.1158/1078-0432.CCR-20-3316. Epub 2020 Nov 18. Clin Cancer Res. 2021. PMID: 33208343 Free PMC article.
Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer.
Börcsök J, Diossy M, Sztupinszki Z, Prosz A, Tisza V, Spisak S, Rusz O, Stormoen DR, Pappot H, Csabai I, Brunak S, Mouw KW, Szallasi Z. Börcsök J, et al. Among authors: tisza v. Clin Cancer Res. 2021 Jul 1;27(13):3734-3743. doi: 10.1158/1078-0432.CCR-20-5037. Epub 2021 May 4. Clin Cancer Res. 2021. PMID: 33947694 Free PMC article.
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma.
Nassar AH, Abou Alaiwi S, Baca SC, Adib E, Corona RI, Seo JH, Fonseca MAS, Spisak S, El Zarif T, Tisza V, Braun DA, Du H, He M, Flaifel A, Alchoueiry M, Denize T, Matar SG, Acosta A, Shukla S, Hou Y, Steinharter J, Bouchard G, Berchuck JE, O'Connor E, Bell C, Nuzzo PV, Mary Lee GS, Signoretti S, Hirsch MS, Pomerantz M, Henske E, Gusev A, Lawrenson K, Choueiri TK, Kwiatkowski DJ, Freedman ML. Nassar AH, et al. Among authors: tisza v. Nat Commun. 2023 Jan 21;14(1):346. doi: 10.1038/s41467-023-35833-5. Nat Commun. 2023. PMID: 36681680 Free PMC article.
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma.
Prosz A, Duan H, Tisza V, Sahgal P, Topka S, Klus GT, Börcsök J, Sztupinszki Z, Hanlon T, Diossy M, Vizkeleti L, Stormoen DR, Csabai I, Pappot H, Vijai J, Offit K, Ried T, Sethi N, Mouw KW, Spisak S, Pathania S, Szallasi Z. Prosz A, et al. Among authors: tisza v. bioRxiv [Preprint]. 2023 Feb 7:2023.02.07.527498. doi: 10.1101/2023.02.07.527498. bioRxiv. 2023. Update in: Sci Rep. 2023 Nov 23;13(1):20567. doi: 10.1038/s41598-023-47946-4 PMID: 36798363 Free PMC article. Updated. Preprint.
Replicative stress in gastroesophageal adenocarcinoma is associated with chromosomal instability and sensitivity to DNA damage response inhibitors.
Sahgal P, Patil DT, Sztupinszki ZM, Tisza V, Spisak S, Huffman B, Prosz A, Singh H, Lazaro JB, Szallasi Z, Cleary JM, Sethi NS. Sahgal P, et al. Among authors: tisza v. bioRxiv [Preprint]. 2023 Mar 28:2023.03.27.534412. doi: 10.1101/2023.03.27.534412. bioRxiv. 2023. Update in: iScience. 2023 Oct 12;26(11):108169. doi: 10.1016/j.isci.2023.108169 PMID: 37034740 Free PMC article. Updated. Preprint.
A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus.
Spisak S, Tisza V, Nuzzo PV, Seo JH, Pataki B, Ribli D, Sztupinszki Z, Bell C, Rohanizadegan M, Stillman DR, Alaiwi SA, Bartels AH, Papp M, Shetty A, Abbasi F, Lin X, Lawrenson K, Gayther SA, Pomerantz M, Baca S, Solymosi N, Csabai I, Szallasi Z, Gusev A, Freedman ML. Spisak S, et al. Among authors: tisza v. Nat Commun. 2023 Aug 23;14(1):5118. doi: 10.1038/s41467-023-40616-z. Nat Commun. 2023. PMID: 37612286 Free PMC article.
35 results