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IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models.
Forbester JL, Clement M, Wellington D, Yeung A, Dimonte S, Marsden M, Chapman L, Coomber EL, Tolley C, Lees E, Hale C, Clare S, Udalova I, Dong T, Dougan G, Humphreys IR. Forbester JL, et al. Among authors: wellington d. J Virol. 2020 Apr 16;94(9):e00121-20. doi: 10.1128/JVI.00121-20. Print 2020 Apr 16. J Virol. 2020. PMID: 32075938 Free PMC article.
Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection.
Makvandi-Nejad S, Laurenson-Schafer H, Wang L, Wellington D, Zhao Y, Jin B, Qin L, Kite K, Moghadam HK, Song C, Clark K, Hublitz P, Townsend AR, Wu H, McMichael AJ, Zhang Y, Dong T. Makvandi-Nejad S, et al. Among authors: wellington d. J Infect Dis. 2018 Jan 4;217(2):257-262. doi: 10.1093/infdis/jix512. J Infect Dis. 2018. PMID: 29202190
High Level Antibody Response to Pandemic Influenza H1N1/09 Virus Is Associated With Interferon-Induced Transmembrane Protein-3 rs12252-CC in Young Adults.
Qin L, Wang D, Li D, Zhao Y, Peng Y, Wellington D, Dai Y, Sun H, Sun J, Liu G, McMichael A, Dong T, Zhang Y. Qin L, et al. Among authors: wellington d. Front Cell Infect Microbiol. 2018 May 15;8:134. doi: 10.3389/fcimb.2018.00134. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 29868492 Free PMC article.
IFITM3-specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans.
Wellington D, Yin Z, Abdel-Haq A, Zhang L, Forbester J, Kite K, Rajapaksa U, Laurenson-Schafer H, Makvandi-Nejad S, Jin B, Bowes E, Manoharan K, Maldonado-Perez D, Verrill C, Humphreys IR, Dong T. Wellington D, et al. Eur J Immunol. 2021 Mar;51(3):742-745. doi: 10.1002/eji.202048706. Epub 2020 Dec 9. Eur J Immunol. 2021. PMID: 33125710 Free PMC article.
An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Peng Y, Felce SL, Dong D, Penkava F, Mentzer AJ, Yao X, Liu G, Yin Z, Chen JL, Lu Y, Wellington D, Wing PAC, Dominey-Foy DCC, Jin C, Wang W, Hamid MA, Fernandes RA, Wang B, Fries A, Zhuang X, Ashley N, Rostron T, Waugh C, Sopp P, Hublitz P, Beveridge R, Tan TK, Dold C, Kwok AJ, Rich-Griffin C, Dejnirattisa W, Liu C, Kurupati P, Nassiri I, Watson RA, Tong O, Taylor CA, Kumar Sharma P, Sun B, Curion F, Revale S, Garner LC, Jansen K, Ferreira RC, Attar M, Fry JW, Russell RA; COMBAT Consortium; Stauss HJ, James W, Townsend A, Ho LP, Klenerman P, Mongkolsapaya J, Screaton GR, Dendrou C, Sansom SN, Bashford-Rogers R, Chain B, Smith GL, McKeating JA, Fairfax BP, Bowness P, McMichael AJ, Ogg G, Knight JC, Dong T. Peng Y, et al. Among authors: wellington d. Nat Immunol. 2022 Jan;23(1):50-61. doi: 10.1038/s41590-021-01084-z. Epub 2021 Dec 1. Nat Immunol. 2022. PMID: 34853448 Free PMC article.
IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.
Clement M, Forbester JL, Marsden M, Sabberwal P, Sommerville MS, Wellington D, Dimonte S, Clare S, Harcourt K, Yin Z, Nobre L, Antrobus R, Jin B, Chen M, Makvandi-Nejad S, Lindborg JA, Strittmatter SM, Weekes MP, Stanton RJ, Dong T, Humphreys IR. Clement M, et al. Among authors: wellington d. Nat Commun. 2022 Sep 8;13(1):5294. doi: 10.1038/s41467-022-32587-4. Nat Commun. 2022. PMID: 36075894 Free PMC article.
T cells are ready for the fight against monkeypox.
Wellington D, Dong T. Wellington D, et al. Cell Host Microbe. 2022 Dec 14;30(12):1653-1654. doi: 10.1016/j.chom.2022.11.004. Cell Host Microbe. 2022. PMID: 36521439 Free PMC article.
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination.
Yin Z, Chen JL, Lu Y, Wang B, Godfrey L, Mentzer AJ, Yao X, Liu G, Wellington D, Zhao Y, Wing PAC, Dejnirattisa W, Supasa P, Liu C, Hublitz P, Beveridge R, Waugh C, Clark SA, Clark K, Sopp P, Rostron T, Mongkolsapaya J, Screaton GR, Ogg G, Ewer K, Pollard AJ, Gilbert S, Knight JC, Lambe T, Smith GL, Dong T, Peng Y. Yin Z, et al. Among authors: wellington d. Cell Rep. 2023 May 30;42(5):112470. doi: 10.1016/j.celrep.2023.112470. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37141092 Free PMC article.
54 results