DeChristopher B - Search Results

1

A Phenotypic Screen Identifies Calcium Overload as a Key Mechanism of β-Cell Glucolipotoxicity.

Vogel J, Yin J, Su L, Wang SX, Zessis R, Fowler S, Chiu CH, Wilson AC, Chen A, Zecri F, Turner G, Smith TM, DeChristopher B, Xing H, Rothman DM, Cai X, Berdichevsky A. Vogel J, et al. Among authors: dechristopher b. Diabetes. 2020 May;69(5):1032-1041. doi: 10.2337/db19-0813. Epub 2020 Feb 20. Diabetes. 2020. PMID: 32079579

2

Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration.

DeChristopher B, Park SH, Vong L, Bamford D, Cho HH, Duvadie R, Fedolak A, Hogan C, Honda T, Pandey P, Rozhitskaya O, Su L, Tomlinson E, Wallace I. DeChristopher B, et al. Bioorg Med Chem Lett. 2019 Apr 15;29(8):991-994. doi: 10.1016/j.bmcl.2019.02.013. Epub 2019 Feb 11. Bioorg Med Chem Lett. 2019. PMID: 30824200

3

Pharmacological Inhibition of MALT1 Ameliorates Autoimmune Pathogenesis and Can Be Uncoupled From Effects on Regulatory T-Cells.

Biswas S, Chalishazar A, Helou Y, DiSpirito J, DeChristopher B, Chatterjee D, Merselis L, Vincent B, Monroe JG, Rabah D, Long AJ. Biswas S, et al. Among authors: dechristopher b. Front Immunol. 2022 May 9;13:875320. doi: 10.3389/fimmu.2022.875320. eCollection 2022. Front Immunol. 2022. PMID: 35615349 Free PMC article.

4

A Condensed, Scalable Synthesis of Racemic Koningic Acid.

Barbe G, Chai D, Chen B, Guay D, Levesque E, Mancuso J, DeChristopher B. Barbe G, et al. Among authors: dechristopher b. J Org Chem. 2020 May 15;85(10):6788-6793. doi: 10.1021/acs.joc.0c00344. Epub 2020 May 4. J Org Chem. 2020. PMID: 32312046

5

Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents.

Marsden MD, Wu X, Navab SM, Loy BA, Schrier AJ, DeChristopher BA, Shimizu AJ, Hardman CT, Ho S, Ramirez CM, Wender PA, Zack JA. Marsden MD, et al. Among authors: dechristopher ba. Virology. 2018 Jul;520:83-93. doi: 10.1016/j.virol.2018.05.006. Epub 2018 May 26. Virology. 2018. PMID: 29800728 Free PMC article.

6

Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.

Wender PA, Baryza JL, Brenner SE, DeChristopher BA, Loy BA, Schrier AJ, Verma VA. Wender PA, et al. Among authors: dechristopher ba. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6721-6. doi: 10.1073/pnas.1015270108. Epub 2011 Mar 17. Proc Natl Acad Sci U S A. 2011. PMID: 21415363 Free PMC article.

7

Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.

DeChristopher BA, Loy BA, Marsden MD, Schrier AJ, Zack JA, Wender PA. DeChristopher BA, et al. Nat Chem. 2012 Sep;4(9):705-10. doi: 10.1038/nchem.1395. Epub 2012 Jul 15. Nat Chem. 2012. PMID: 22914190 Free PMC article.

8

Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.

Staveness D, Abdelnabi R, Schrier AJ, Loy BA, Verma VA, DeChristopher BA, Near KE, Neyts J, Delang L, Leyssen P, Wender PA. Staveness D, et al. Among authors: dechristopher ba. J Nat Prod. 2016 Apr 22;79(4):675-9. doi: 10.1021/acs.jnatprod.5b01016. Epub 2016 Feb 22. J Nat Prod. 2016. PMID: 26900625 Free PMC article.

9

Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy.

Wender PA, Dechristopher BA, Schrier AJ. Wender PA, et al. Among authors: dechristopher ba. J Am Chem Soc. 2008 May 28;130(21):6658-9. doi: 10.1021/ja8015632. Epub 2008 May 2. J Am Chem Soc. 2008. PMID: 18452292 Free PMC article.

10

"Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.

DeChristopher BA, Fan AC, Felsher DW, Wender PA. DeChristopher BA, et al. Oncotarget. 2012 Jan;3(1):58-66. doi: 10.18632/oncotarget.438. Oncotarget. 2012. PMID: 22308267 Free PMC article.

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