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Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma.
Zhang Y, Zvi YS, Batko B, Zaphiros N, O'Donnell EF, Wang J, Sato K, Yang R, Geller DS, Koirala P, Zhang W, Du X, Piperdi S, Liu Y, Zheng D, Roth M, Gill J, Zhang J, Ren T, Gorlick R, Zi X, Hoang BH. Zhang Y, et al. Among authors: wang j. Sci Rep. 2018 Sep 24;8(1):14294. doi: 10.1038/s41598-018-32428-9. Sci Rep. 2018. PMID: 30250282 Free PMC article.
Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma.
Wang J, Sato K, O'Donnell E, Singla A, Yaguare S, Aldahamsheh O, Batko B, Borjihan H, Tingling J, Zhang J, Weiser DA, Loeb DM, Gorlick R, Schwartz EL, Yang R, Zi X, Zhao H, Geller DS, Hoang BH. Wang J, et al. Transl Oncol. 2020 Oct;13(10):100809. doi: 10.1016/j.tranon.2020.100809. Epub 2020 Jul 2. Transl Oncol. 2020. PMID: 32623326 Free PMC article.
Wnt Signaling in Osteosarcoma.
Singla A, Wang J, Yang R, Geller DS, Loeb DM, Hoang BH. Singla A, et al. Among authors: wang j. Adv Exp Med Biol. 2020;1258:125-139. doi: 10.1007/978-3-030-43085-6_8. Adv Exp Med Biol. 2020. PMID: 32767238 Review.
The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma.
Wang J, Aldahamsheh O, Ferrena A, Borjihan H, Singla A, Yaguare S, Singh S, Viscarret V, Tingling J, Zi X, Lo Y, Gorlick R, Zheng D, Schwartz EL, Zhao H, Yang R, Geller DS, Hoang BH. Wang J, et al. Ann N Y Acad Sci. 2021 Apr;1490(1):90-104. doi: 10.1111/nyas.14578. Epub 2021 Feb 16. Ann N Y Acad Sci. 2021. PMID: 33594717 Free PMC article.
SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosis.
Ferrena A, Wang J, Zhang R, Karadal-Ferrena B, Al-Hardan W, Singh S, Borjihan H, Schwartz E, Zhao H, Yang R, Geller D, Hoang B, Zheng D. Ferrena A, et al. Among authors: wang j. bioRxiv [Preprint]. 2023 May 12:2023.05.09.540053. doi: 10.1101/2023.05.09.540053. bioRxiv. 2023. Update in: Mol Cancer Ther. 2024 Feb 1;23(2):223-234. doi: 10.1158/1535-7163.MCT-23-0173 PMID: 37214958 Free PMC article. Updated. Preprint.
Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma.
Wang J, Ferrena A, Zhang R, Singh S, Viscarret V, Al-Harden W, Aldahamsheh O, Borjihan H, Singla A, Yaguare S, Tingling J, Zi X, Lo Y, Gorlick R, Schwartz EL, Zhao H, Yang R, Geller DS, Zheng D, Hoang BH. Wang J, et al. Oncogene. 2024 Mar;43(13):962-975. doi: 10.1038/s41388-024-02942-4. Epub 2024 Feb 14. Oncogene. 2024. PMID: 38355807 Free PMC article.
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