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Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo.
Oncotarget. 2020 Feb 4;11(5):493-509. doi: 10.18632/oncotarget.27380. eCollection 2020 Feb 4.
Oncotarget. 2020.
PMID: 32082484
Free PMC article.
Vitamin D receptor agonists regulate ocular developmental angiogenesis and modulate expression of dre-miR-21 and VEGF.
Merrigan SL, Kennedy BN.
Merrigan SL, et al.
Br J Pharmacol. 2017 Aug;174(16):2636-2651. doi: 10.1111/bph.13875. Epub 2017 Jul 7.
Br J Pharmacol. 2017.
PMID: 28547797
Free PMC article.
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A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy.
Sulaiman RS, Merrigan S, Quigley J, Qi X, Lee B, Boulton ME, Kennedy B, Seo SY, Corson TW.
Sulaiman RS, et al.
Sci Rep. 2016 May 5;6:25509. doi: 10.1038/srep25509.
Sci Rep. 2016.
PMID: 27148944
Free PMC article.
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Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis.
Reynolds AL, Alvarez Y, Sasore T, Waghorne N, Butler CT, Kilty C, Smith AJ, McVicar C, Wong VH, Galvin O, Merrigan S, Osman J, Grebnev G, Sjölander A, Stitt AW, Kennedy BN.
Reynolds AL, et al.
J Biol Chem. 2016 Apr 1;291(14):7242-55. doi: 10.1074/jbc.M115.710665. Epub 2016 Feb 4.
J Biol Chem. 2016.
PMID: 26846851
Free PMC article.
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