Maspin binds to cardiolipin in mitochondria and triggers apoptosis.
Mahajan N, Hoover B, Rajendram M, Shi HY, Kawasaki K, Weibel DB, Zhang M.
Mahajan N, et al.
FASEB J. 2019 May;33(5):6354-6364. doi: 10.1096/fj.201802182R. Epub 2019 Feb 20.
FASEB J. 2019.
PMID: 30786218
Free PMC article.
We propose a model of apoptosis in which maspin binds to cardiolipin, displaces cytochrome c from the membrane, and facilitates its release to the cytoplasm.-Mahajan, N., Hoover, B., Rajendram, M., Shi, H. Y., Kawasaki, K., Weibel, D. B., Zhang, M. ...
We propose a model of apoptosis in which maspin binds to cardiolipin, displaces cytochrome c from the membrane, and facilitates its release …