Sim T - Search Results

1

Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy.

Choi JW , Choi SH , Hong ST , Kim MS , Ryu SS , Yoon YU , Paik KC , Han MS , Sim T , Cho BR . Choi JW , et al. Among authors: sim t. Chem Commun (Camb). 2020 Mar 28;56(25):3657-3660. doi: 10.1039/d0cc00236d. Epub 2020 Feb 28. Chem Commun (Camb). 2020. PMID: 32108200

2

A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.

Yoon H, Kwak Y, Choi S, Cho H, Kim ND, Sim T. Yoon H, et al. Among authors: sim t. J Med Chem. 2016 Jan 14;59(1):358-73. doi: 10.1021/acs.jmedchem.5b01522. Epub 2015 Dec 22. J Med Chem. 2016. PMID: 26652860

3

First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.

Cho H, Shin I, Ju E, Choi S, Hur W, Kim H, Hong E, Kim ND, Choi HG, Gray NS, Sim T. Cho H, et al. Among authors: sim t. J Med Chem. 2018 Sep 27;61(18):8353-8373. doi: 10.1021/acs.jmedchem.8b00882. Epub 2018 Sep 11. J Med Chem. 2018. PMID: 30153003

4

Suppression of TRPM7 enhances TRAIL-induced apoptosis in triple-negative breast cancer cells.

Song C, Choi S, Oh KB, Sim T. Song C, et al. Among authors: sim t. J Cell Physiol. 2020 Dec;235(12):10037-10050. doi: 10.1002/jcp.29820. Epub 2020 May 29. J Cell Physiol. 2020. PMID: 32468675

5

The first small molecules capable of strongly suppressing proliferation of cancer cells harboring BRAF class I/II/III mutations.

Choi SH, Shin I, Kim N, Nam Y, Sim T. Choi SH, et al. Among authors: sim t. Biochem Biophys Res Commun. 2020 Nov 5;532(2):315-320. doi: 10.1016/j.bbrc.2020.07.110. Epub 2020 Aug 30. Biochem Biophys Res Commun. 2020. PMID: 32873393

6

Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers.

Choi SH, Ryu S, Sim K, Song C, Shin I, Kim SS, Lee YS, Park JY, Sim T. Choi SH, et al. Among authors: sim k, sim t. Eur J Med Chem. 2020 Dec 15;208:112688. doi: 10.1016/j.ejmech.2020.112688. Epub 2020 Aug 8. Eur J Med Chem. 2020. PMID: 32906067

7

A new quantum dot-platinum conjugate for self-assembled nanoconjugates by coordination bonding mediated recognition.

Lee J, Kim H, Sim T, Song R. Lee J, et al. Among authors: sim t. Chem Commun (Camb). 2013 Jul 14;49(55):6182-4. doi: 10.1039/c3cc42245c. Chem Commun (Camb). 2013. PMID: 23732395

8

Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs.

Bang EK, Cho H, Jeon SS, Tran NL, Lim DK, Hur W, Sim T. Bang EK, et al. Among authors: sim t. Chem Biol Drug Des. 2018 Feb;91(2):575-587. doi: 10.1111/cbdd.13122. Epub 2017 Nov 13. Chem Biol Drug Des. 2018. PMID: 29052961

9

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.

Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS. Wang J, et al. Among authors: sim t. ACS Chem Biol. 2018 Sep 21;13(9):2438-2448. doi: 10.1021/acschembio.7b00638. Epub 2018 Aug 31. ACS Chem Biol. 2018. PMID: 30102854 Free PMC article.

10

Targeted kinase degradation via the KLHDC2 ubiquitin E3 ligase.

Kim Y, Seo P, Jeon E, You I, Hwang K, Kim N, Tse J, Bae J, Choi HS, Hinshaw SM, Gray NS, Sim T. Kim Y, et al. Among authors: sim t. Cell Chem Biol. 2023 Nov 16;30(11):1414-1420.e5. doi: 10.1016/j.chembiol.2023.07.008. Epub 2023 Aug 10. Cell Chem Biol. 2023. PMID: 37567174 Free PMC article.

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