Malumbres M - Search Results

1

CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.

Salvador-Barbero B, Álvarez-Fernández M, Zapatero-Solana E, El Bakkali A, Menéndez MDC, López-Casas PP, Di Domenico T, Xie T, VanArsdale T, Shields DJ, Hidalgo M, Malumbres M. Salvador-Barbero B, et al. Among authors: malumbres m. Cancer Cell. 2020 Mar 16;37(3):340-353.e6. doi: 10.1016/j.ccell.2020.01.007. Epub 2020 Feb 27. Cancer Cell. 2020. PMID: 32109375 Free article.

2

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6.

Malumbres M, Sotillo R, Santamaría D, Galán J, Cerezo A, Ortega S, Dubus P, Barbacid M. Malumbres M, et al. Cell. 2004 Aug 20;118(4):493-504. doi: 10.1016/j.cell.2004.08.002. Cell. 2004. PMID: 15315761 Free article.

3

Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity.

Sotillo R, Renner O, Dubus P, Ruiz-Cabello J, Martín-Caballero J, Barbacid M, Carnero A, Malumbres M. Sotillo R, et al. Among authors: malumbres m. Cancer Res. 2005 May 1;65(9):3846-52. doi: 10.1158/0008-5472.CAN-04-4195. Cancer Res. 2005. PMID: 15867383

4

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

Martín A, Odajima J, Hunt SL, Dubus P, Ortega S, Malumbres M, Barbacid M. Martín A, et al. Among authors: malumbres m. Cancer Cell. 2005 Jun;7(6):591-8. doi: 10.1016/j.ccr.2005.05.006. Cancer Cell. 2005. PMID: 15950907 Free article.

5

Is Cyclin D1-CDK4 kinase a bona fide cancer target?

Malumbres M, Barbacid M. Malumbres M, et al. Cancer Cell. 2006 Jan;9(1):2-4. doi: 10.1016/j.ccr.2005.12.026. Cancer Cell. 2006. PMID: 16413464 Free article.

6

Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression.

Quereda V, Martinalbo J, Dubus P, Carnero A, Malumbres M. Quereda V, et al. Among authors: malumbres m. Oncogene. 2007 Dec 6;26(55):7665-74. doi: 10.1038/sj.onc.1210578. Epub 2007 Jun 18. Oncogene. 2007. PMID: 17599058

7

Cyclins and related kinases in cancer cells.

Malumbres M. Malumbres M. J BUON. 2007 Sep;12 Suppl 1:S45-52. J BUON. 2007. PMID: 17935277 Review.

8

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.

Manchado E, Guillamot M, de Cárcer G, Eguren M, Trickey M, García-Higuera I, Moreno S, Yamano H, Cañamero M, Malumbres M. Manchado E, et al. Among authors: malumbres m. Cancer Cell. 2010 Dec 14;18(6):641-54. doi: 10.1016/j.ccr.2010.10.028. Cancer Cell. 2010. PMID: 21156286 Free article.

9

Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals.

Álvarez-Fernández M, Sánchez-Martínez R, Sanz-Castillo B, Gan PP, Sanz-Flores M, Trakala M, Ruiz-Torres M, Lorca T, Castro A, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17374-9. doi: 10.1073/pnas.1310745110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101512 Free PMC article.

10

A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.

Eguren M, Álvarez-Fernández M, García F, López-Contreras AJ, Fujimitsu K, Yaguchi H, Luque-García JL, Fernández-Capetillo O, Muñoz J, Yamano H, Malumbres M. Eguren M, et al. Among authors: malumbres m. Cell Rep. 2014 Feb 27;6(4):670-83. doi: 10.1016/j.celrep.2014.01.017. Epub 2014 Feb 6. Cell Rep. 2014. PMID: 24508461 Free article.

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