Pavelko K - Search Results

1

Targeted Apoptosis of Ductular Reactive Cells Reduces Hepatic Fibrosis in a Mouse Model of Cholestasis.

Azad AI, Krishnan A, Troop L, Li Y, Katsumi T, Pavelko K, Kostallari E, Guicciardi ME, Gores GJ. Azad AI, et al. Among authors: pavelko k. Hepatology. 2020 Sep;72(3):1013-1028. doi: 10.1002/hep.31211. Hepatology. 2020. PMID: 32128842 Free PMC article.

2

Integrin β₁-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH.

Guo Q, Furuta K, Lucien F, Gutierrez Sanchez LH, Hirsova P, Krishnan A, Kabashima A, Pavelko KD, Madden B, Alhuwaish H, Gao Y, Revzin A, Ibrahim SH. Guo Q, et al. Among authors: pavelko kd. J Hepatol. 2019 Dec;71(6):1193-1205. doi: 10.1016/j.jhep.2019.07.019. Epub 2019 Aug 6. J Hepatol. 2019. PMID: 31433301 Free PMC article.

3

IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis.

Dasgupta D, Nakao Y, Mauer AS, Thompson JM, Sehrawat TS, Liao CY, Krishnan A, Lucien F, Guo Q, Liu M, Xue F, Fukushima M, Katsumi T, Bansal A, Pandey MK, Maiers JL, DeGrado T, Ibrahim SH, Revzin A, Pavelko KD, Barry MA, Kaufman RJ, Malhi H. Dasgupta D, et al. Among authors: pavelko kd. Gastroenterology. 2020 Oct;159(4):1487-1503.e17. doi: 10.1053/j.gastro.2020.06.031. Epub 2020 Jun 20. Gastroenterology. 2020. PMID: 32574624 Free PMC article.

4

Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma.

Loeuillard E, Yang J, Buckarma E, Wang J, Liu Y, Conboy C, Pavelko KD, Li Y, O'Brien D, Wang C, Graham RP, Smoot RL, Dong H, Ilyas S. Loeuillard E, et al. J Clin Invest. 2020 Oct 1;130(10):5380-5396. doi: 10.1172/JCI137110. J Clin Invest. 2020. PMID: 32663198 Free PMC article.

5

Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis.

Furuta K, Guo Q, Pavelko KD, Lee JH, Robertson KD, Nakao Y, Melek J, Shah VH, Hirsova P, Ibrahim SH. Furuta K, et al. Among authors: pavelko kd. J Clin Invest. 2021 Mar 15;131(6):e143690. doi: 10.1172/JCI143690. J Clin Invest. 2021. PMID: 33476308 Free PMC article.

6

TCF-1 controls T_reg cell functions that regulate inflammation, CD8⁺ T cell cytotoxicity and severity of colon cancer.

Osman A, Yan B, Li Y, Pavelko KD, Quandt J, Saadalla A, Singh MP, Kazemian M, Gounari F, Khazaie K. Osman A, et al. Among authors: pavelko kd. Nat Immunol. 2021 Sep;22(9):1152-1162. doi: 10.1038/s41590-021-00987-1. Epub 2021 Aug 12. Nat Immunol. 2021. PMID: 34385712 Free PMC article.

7

Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis.

Dohnalkova E, Bayer RL, Guo Q, Bamidele AO, Kim Lee HS, Valenzuela-Pérez L, Krishnan A, Pavelko KD, Guisot NES, Bunyard P, Kim YB, Ibrahim SH, Gores GJ, Hirsova P. Dohnalkova E, et al. Among authors: pavelko kd. Hepatol Commun. 2023 Jun 2;7(6):e0171. doi: 10.1097/HC9.0000000000000171. eCollection 2023 Jun 1. Hepatol Commun. 2023. PMID: 37267252 Free PMC article.

8

Macrophage RAGE activation is proinflammatory in NASH.

Parthasarathy G, Mauer AS, Golla N, Daniel PV, Kim LH, Sidhu GS, Marek GW 3rd, Loeuillard E, Krishnan A, Lee HSK, Pavelko KD, Charlton M, Hirsova P, Ilyas SI, Malhi H. Parthasarathy G, et al. Among authors: pavelko kd. JCI Insight. 2024 Feb 8;9(3):e169138. doi: 10.1172/jci.insight.169138. JCI Insight. 2024. PMID: 38175729 Free PMC article.

9

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) deletion in myeloid cells augments cholestatic liver injury.

Krishnan A, Ozturk NB, Cutshaw KA, Guicciardi ME, Kitagataya T, Olson KE, Pavelko KD, Sherman W, Wixom AQ, Jalan-Sakrikar N, Baez-Faria M, Gutierrez F, Gores GJ. Krishnan A, et al. Among authors: pavelko kd. Sci Rep. 2024 Jan 25;14(1):2145. doi: 10.1038/s41598-024-52710-3. Sci Rep. 2024. PMID: 38273071 Free PMC article.

10

Recombinant human IL-6 suppresses demyelination in a viral model of multiple sclerosis.

Rodriguez M, Pavelko KD, McKinney CW, Leibowitz JL. Rodriguez M, et al. Among authors: pavelko kd. J Immunol. 1994 Oct 15;153(8):3811-21. J Immunol. 1994. PMID: 7930598

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