Goedeke L - Search Results

1

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.

Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI. Perry RJ, et al. Among authors: goedeke l. Nature. 2020 Mar;579(7798):279-283. doi: 10.1038/s41586-020-2074-6. Epub 2020 Mar 4. Nature. 2020. PMID: 32132708 Free PMC article.

2

Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression.

Fernández-Tussy P, Sun J, Cardelo MP, Price NL, Goedeke L, Xirouchaki CE, Yang X, Pastor-Rojo O, Bennett AM, Tiganis T, Suárez Y, Fernández-Hernando C. Fernández-Tussy P, et al. Among authors: goedeke l. bioRxiv [Preprint]. 2023 Jan 20:2023.01.18.523503. doi: 10.1101/2023.01.18.523503. bioRxiv. 2023. Update in: JCI Insight. 2024 Aug 27;9(19):e168476. doi: 10.1172/jci.insight.168476 PMID: 36711578 Free PMC article. Updated. Preprint.

3

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance.

Price NL, Singh AK, Rotllan N, Goedeke L, Wing A, Canfrán-Duque A, Diaz-Ruiz A, Araldi E, Baldán Á, Camporez JP, Suárez Y, Rodeheffer MS, Shulman GI, de Cabo R, Fernández-Hernando C. Price NL, et al. Among authors: goedeke l. Cell Rep. 2018 Feb 20;22(8):2133-2145. doi: 10.1016/j.celrep.2018.01.074. Cell Rep. 2018. PMID: 29466739 Free PMC article.

4

Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.

Vatner DF, Goedeke L, Camporez JG, Lyu K, Nasiri AR, Zhang D, Bhanot S, Murray SF, Still CD, Gerhard GS, Shulman GI, Samuel VT. Vatner DF, et al. Among authors: goedeke l. Diabetologia. 2018 Jun;61(6):1435-1446. doi: 10.1007/s00125-018-4579-1. Epub 2018 Mar 1. Diabetologia. 2018. PMID: 29497783 Free PMC article.

5

Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C. Aryal B, et al. Among authors: goedeke l. JCI Insight. 2018 Mar 22;3(6):e97918. doi: 10.1172/jci.insight.97918. JCI Insight. 2018. PMID: 29563332 Free PMC article.

6

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.

Goedeke L, Bates J, Vatner DF, Perry RJ, Wang T, Ramirez R, Li L, Ellis MW, Zhang D, Wong KE, Beysen C, Cline GW, Ray AS, Shulman GI. Goedeke L, et al. Hepatology. 2018 Dec;68(6):2197-2211. doi: 10.1002/hep.30097. Hepatology. 2018. PMID: 29790582 Free PMC article.

7

Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes.

Goedeke L, Perry RJ, Shulman GI. Goedeke L, et al. Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:65-87. doi: 10.1146/annurev-pharmtox-010716-104727. Annu Rev Pharmacol Toxicol. 2019. PMID: 30625285 Free PMC article. Review.

8

Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates.

Goedeke L, Peng L, Montalvo-Romeral V, Butrico GM, Dufour S, Zhang XM, Perry RJ, Cline GW, Kievit P, Chng K, Petersen KF, Shulman GI. Goedeke L, et al. Sci Transl Med. 2019 Oct 2;11(512):eaay0284. doi: 10.1126/scitranslmed.aay0284. Sci Transl Med. 2019. PMID: 31578240 Free PMC article.

9

Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice.

Li X, Zhang D, Vatner DF, Goedeke L, Hirabara SM, Zhang Y, Perry RJ, Shulman GI. Li X, et al. Among authors: goedeke l. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32584-32593. doi: 10.1073/pnas.1922169117. Epub 2020 Dec 8. Proc Natl Acad Sci U S A. 2020. PMID: 33293421 Free PMC article.

10

Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH.

Goedeke L, Shulman GI. Goedeke L, et al. Mol Metab. 2021 Apr;46:101178. doi: 10.1016/j.molmet.2021.101178. Epub 2021 Feb 3. Mol Metab. 2021. PMID: 33545391 Free PMC article. Review.

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