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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease.
Leonard KA, Madge LA, Krawczuk PJ, Wang A, Kreutter KD, Bacani GM, Chai W, Smith RC, Tichenor MS, Harris MC, Malaviya R, Seierstad M, Johnson ME, Venable JD, Kim S, Hirst GC, Mathur AS, Rao TS, Edwards JP, Rizzolio MC, Koudriakova T. Leonard KA, et al. Among authors: krawczuk pj. J Med Chem. 2020 Mar 26;63(6):2915-2929. doi: 10.1021/acs.jmedchem.9b01439. Epub 2020 Mar 16. J Med Chem. 2020. PMID: 32134643
Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes.
Lercher L, Simon N, Bergmann A, Tauchert M, Bochmann D, Bashir T, Neuefeind T, Riley D, Danna B, Krawczuk P, Pande V, Patrick A, Steele R, Wang W, Rupnow B, Tummino P, Sharma S, Finley M. Lercher L, et al. SLAS Discov. 2022 Jul;27(5):306-313. doi: 10.1016/j.slasd.2022.04.003. Epub 2022 May 2. SLAS Discov. 2022. PMID: 35513262 Free article.