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LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, Curtarello M, Silic-Benussi M, Rossi E, Venturoli C, Panieri E, Santoro MM, Di Paolo V, Quintieri L, Ciminale V, Indraccolo S. Zulato E, et al. Among authors: ciccarese f. Biochem Pharmacol. 2018 Oct;156:479-490. doi: 10.1016/j.bcp.2018.09.019. Epub 2018 Sep 15. Biochem Pharmacol. 2018. PMID: 30222967
Comprehensive Profiling of Hypoxia-Related miRNAs Identifies miR-23a-3p Overexpression as a Marker of Platinum Resistance and Poor Prognosis in High-Grade Serous Ovarian Cancer.
Todeschini P, Salviato E, Romani C, Raimondi V, Ciccarese F, Ferrari F, Tognon G, Marchini S, D'Incalci M, Zanotti L, Ravaggi A, Odicino F, Sartori E, D'Agostino DM, Samaja M, Romualdi C, Bignotti E. Todeschini P, et al. Among authors: ciccarese f. Cancers (Basel). 2021 Jul 4;13(13):3358. doi: 10.3390/cancers13133358. Cancers (Basel). 2021. PMID: 34283087 Free PMC article.
mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells.
Silic-Benussi M, Sharova E, Ciccarese F, Cavallari I, Raimondi V, Urso L, Corradin A, Kotler H, Scattolin G, Buldini B, Francescato S, Basso G, Minuzzo SA, Indraccolo S, D'Agostino DM, Ciminale V. Silic-Benussi M, et al. Among authors: ciccarese f. Redox Biol. 2022 May;51:102268. doi: 10.1016/j.redox.2022.102268. Epub 2022 Feb 24. Redox Biol. 2022. PMID: 35248829 Free PMC article.
137 results