Chen B - Search Results

1

HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.

Xiao T, Frey G, Fu Q, Lavine CL, Scott DA, Seaman MS, Chou JJ, Chen B. Xiao T, et al. Among authors: chen b. Nat Chem Biol. 2020 May;16(5):529-537. doi: 10.1038/s41589-020-0496-y. Epub 2020 Mar 9. Nat Chem Biol. 2020. PMID: 32152540 Free PMC article.

2

Structure of an unliganded simian immunodeficiency virus gp120 core.

Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC. Chen B, et al. Nature. 2005 Feb 24;433(7028):834-41. doi: 10.1038/nature03327. Nature. 2005. PMID: 15729334

3

Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion.

Frey G, Rits-Volloch S, Zhang XQ, Schooley RT, Chen B, Harrison SC. Frey G, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13938-43. doi: 10.1073/pnas.0601036103. Epub 2006 Sep 8. Proc Natl Acad Sci U S A. 2006. PMID: 16963566 Free PMC article.

4

Restraining the conformation of HIV-1 gp120 by removing a flexible loop.

Rits-Volloch S, Frey G, Harrison SC, Chen B. Rits-Volloch S, et al. Among authors: chen b. EMBO J. 2006 Oct 18;25(20):5026-35. doi: 10.1038/sj.emboj.7601358. Epub 2006 Sep 28. EMBO J. 2006. PMID: 17006538 Free PMC article.

5

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies.

Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, Chen B. Frey G, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3739-44. doi: 10.1073/pnas.0800255105. Epub 2008 Mar 5. Proc Natl Acad Sci U S A. 2008. PMID: 18322015 Free PMC article.

6

Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs.

Nkolola JP, Peng H, Settembre EC, Freeman M, Grandpre LE, Devoy C, Lynch DM, La Porte A, Simmons NL, Bradley R, Montefiori DC, Seaman MS, Chen B, Barouch DH. Nkolola JP, et al. Among authors: chen b. J Virol. 2010 Apr;84(7):3270-9. doi: 10.1128/JVI.02252-09. Epub 2010 Jan 6. J Virol. 2010. PMID: 20053749 Free PMC article.

7

Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.

Frey G, Chen J, Rits-Volloch S, Freeman MM, Zolla-Pazner S, Chen B. Frey G, et al. Among authors: chen j, chen b. Nat Struct Mol Biol. 2010 Dec;17(12):1486-91. doi: 10.1038/nsmb.1950. Epub 2010 Nov 14. Nat Struct Mol Biol. 2010. PMID: 21076402 Free PMC article.

8

Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody.

Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Freeman MM, et al. Among authors: chen b. Structure. 2010 Dec 8;18(12):1632-41. doi: 10.1016/j.str.2010.09.017. Structure. 2010. PMID: 21134642 Free PMC article.

9

HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.

Kovacs JM, Nkolola JP, Peng H, Cheung A, Perry J, Miller CA, Seaman MS, Barouch DH, Chen B. Kovacs JM, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12111-6. doi: 10.1073/pnas.1204533109. Epub 2012 Jul 5. Proc Natl Acad Sci U S A. 2012. PMID: 22773820 Free PMC article.

10

Mechanism of HIV-1 neutralization by antibodies targeting a membrane-proximal region of gp41.

Chen J, Frey G, Peng H, Rits-Volloch S, Garrity J, Seaman MS, Chen B. Chen J, et al. Among authors: chen b. J Virol. 2014 Jan;88(2):1249-58. doi: 10.1128/JVI.02664-13. Epub 2013 Nov 13. J Virol. 2014. PMID: 24227838 Free PMC article.

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