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25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.
Trousson A, Bernard S, Petit PX, Liere P, Pianos A, El Hadri K, Lobaccaro JM, Ghandour MS, Raymondjean M, Schumacher M, Massaad C. Trousson A, et al. Among authors: liere p. J Neurochem. 2009 May;109(4):945-58. doi: 10.1111/j.1471-4159.2009.06009.x. Epub 2009 Feb 24. J Neurochem. 2009. PMID: 19250336 Free article.
Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum.
Meffre D, Shackleford G, Hichor M, Gorgievski V, Tzavara ET, Trousson A, Ghoumari AM, Deboux C, Nait Oumesmar B, Liere P, Schumacher M, Baulieu EE, Charbonnier F, Grenier J, Massaad C. Meffre D, et al. Among authors: liere p. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7587-92. doi: 10.1073/pnas.1424951112. Epub 2015 May 28. Proc Natl Acad Sci U S A. 2015. PMID: 26023184 Free PMC article.
A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
Bloms-Funke P, Schumacher M, Liu S, Su D, Li J, Liere P, Rupprecht R, Nothdurfter C, Bahrenberg G, Christoph T, Habermann C, Kneip C, Schröder W, Tzschentke TM, Saunders D. Bloms-Funke P, et al. Among authors: liere p. Eur J Pharmacol. 2022 May 15;923:174935. doi: 10.1016/j.ejphar.2022.174935. Epub 2022 Apr 2. Eur J Pharmacol. 2022. PMID: 35378102
3 Beta-hydroxysteroid dehydrogenase expression in rat spinal cord.
Coirini H, Gouézou M, Liere P, Delespierre B, Pianos A, Eychenne B, Schumacher M, Guennoun R. Coirini H, et al. Among authors: liere p. Neuroscience. 2002;113(4):883-91. doi: 10.1016/s0306-4522(02)00224-5. Neuroscience. 2002. PMID: 12182894
71 results