O'Brien AD - Search Results

1

The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool.

Hauser JR, Atitkar RR, Petro CD, Lindsey RL, Strockbine N, O'Brien AD, Melton-Celsa AR. Hauser JR, et al. Among authors: o brien ad. Front Cell Infect Microbiol. 2020 Feb 26;10:62. doi: 10.3389/fcimb.2020.00062. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32175286 Free PMC article.

2

Pathogenesis of Shiga-toxin producing escherichia coli.

Melton-Celsa A, Mohawk K, Teel L, O'Brien A. Melton-Celsa A, et al. Curr Top Microbiol Immunol. 2012;357:67-103. doi: 10.1007/82_2011_176. Curr Top Microbiol Immunol. 2012. PMID: 21915773 Review.

3

The 13C4 monoclonal antibody that neutralizes Shiga toxin Type 1 (Stx1) recognizes three regions on the Stx1 B subunit and prevents Stx1 from binding to its eukaryotic receptor globotriaosylceramide.

Smith MJ, Carvalho HM, Melton-Celsa AR, O'Brien AD. Smith MJ, et al. Infect Immun. 2006 Dec;74(12):6992-8. doi: 10.1128/IAI.01247-06. Epub 2006 Oct 9. Infect Immun. 2006. PMID: 17030576 Free PMC article.

4

Monoclonal antibody 11E10, which neutralizes shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin.

Smith MJ, Melton-Celsa AR, Sinclair JF, Carvalho HM, Robinson CM, O'Brien AD. Smith MJ, et al. Infect Immun. 2009 Jul;77(7):2730-40. doi: 10.1128/IAI.00005-09. Epub 2009 May 11. Infect Immun. 2009. PMID: 19433543 Free PMC article.

5

Pathogenesis of Escherichia coli O157:H7 strain 86-24 following oral infection of BALB/c mice with an intact commensal flora.

Mohawk KL, Melton-Celsa AR, Zangari T, Carroll EE, O'Brien AD. Mohawk KL, et al. Microb Pathog. 2010 Mar-Apr;48(3-4):131-42. doi: 10.1016/j.micpath.2010.01.003. Epub 2010 Jan 22. Microb Pathog. 2010. PMID: 20096770 Free PMC article.

6

Neutralizing antibodies to Shiga toxin type 2 (Stx2) reduce colonization of mice by Stx2-expressing Escherichia coli O157:H7.

Mohawk KL, Melton-Celsa AR, Robinson CM, O'Brien AD. Mohawk KL, et al. Vaccine. 2010 Jul 5;28(30):4777-85. doi: 10.1016/j.vaccine.2010.04.099. Epub 2010 May 14. Vaccine. 2010. PMID: 20472033 Free PMC article.

7

Human intestinal tissue and cultured colonic cells contain globotriaosylceramide synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide.

Zumbrun SD, Hanson L, Sinclair JF, Freedy J, Melton-Celsa AR, Rodriguez-Canales J, Hanson JC, O'Brien AD. Zumbrun SD, et al. Infect Immun. 2010 Nov;78(11):4488-99. doi: 10.1128/IAI.00620-10. Epub 2010 Aug 23. Infect Immun. 2010. PMID: 20732996 Free PMC article.

8

Virulence of the Shiga toxin type 2-expressing Escherichia coli O104:H4 German outbreak isolate in two animal models.

Zangari T, Melton-Celsa AR, Panda A, Boisen N, Smith MA, Tatarov I, De Tolla LJ, Nataro JP, O'Brien AD. Zangari T, et al. Infect Immun. 2013 May;81(5):1562-74. doi: 10.1128/IAI.01310-12. Epub 2013 Feb 25. Infect Immun. 2013. PMID: 23439303 Free PMC article.

9

Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease.

Zumbrun SD, Melton-Celsa AR, Smith MA, Gilbreath JJ, Merrell DS, O'Brien AD. Zumbrun SD, et al. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):E2126-33. doi: 10.1073/pnas.1222014110. Epub 2013 May 20. Proc Natl Acad Sci U S A. 2013. PMID: 23690602 Free PMC article.

10

When a healthy diet turns deadly.

Zumbrun SD, Melton-Celsa AR, O'Brien AD. Zumbrun SD, et al. Gut Microbes. 2014 Jan-Feb;5(1):40-3. doi: 10.4161/gmic.26263. Epub 2013 Jan 1. Gut Microbes. 2014. PMID: 23989728 Free PMC article.

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