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Page 1
Activity of diphenyl ether benzyl amines against Human African Trypanosomiasis.
Hagen JP, Darner G, Anderson S, Higgins K, Leas DA, Mitra A, Mashinson V, Wol T, Vera-Esquivel C, Belter B, Cal M, Kaiser M, Wallick A, Warner RC, Davis PH. Hagen JP, et al. Among authors: leas da. Bioorg Chem. 2020 Apr;97:103590. doi: 10.1016/j.bioorg.2020.103590. Epub 2020 Jan 27. Bioorg Chem. 2020. PMID: 32179269
Progress in antischistosomal N,N'-diaryl urea SAR.
Wu J, Wang C, Leas D, Vargas M, White KL, Shackleford DM, Chen G, Sanford AG, Hemsley RM, Davis PH, Dong Y, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. Bioorg Med Chem Lett. 2018 Feb 1;28(3):244-248. doi: 10.1016/j.bmcl.2017.12.064. Epub 2017 Dec 29. Bioorg Med Chem Lett. 2018. PMID: 29317164 Free PMC article.
Diaryl Ureas as an Antiprotozoal Chemotype.
Leas DA, Sanford AG, Wu J, Cal M, Kaiser M, Wittlin S, Hemsley RM, Darner EB, Lui LM, Davis PH, Vennerstrom JL. Leas DA, et al. ACS Infect Dis. 2021 Jun 11;7(6):1578-1583. doi: 10.1021/acsinfecdis.1c00135. Epub 2021 May 10. ACS Infect Dis. 2021. PMID: 33971090 Free PMC article.
Antischistosomal tetrahydro-γ-carboline sulfonamides.
Ren R, Wang X, Leas DA, Häberli C, Cal M, Dong Y, Kaiser M, Keiser J, Vennerstrom JL. Ren R, et al. Among authors: leas da. Bioorg Med Chem Lett. 2022 Mar 1;59:128546. doi: 10.1016/j.bmcl.2022.128546. Epub 2022 Jan 12. Bioorg Med Chem Lett. 2022. PMID: 35031451 Free PMC article.
Antimalarial Dibenzannulated Medium-Ring Keto Lactams.
Ren R, Wang X, Leas DA, Scheurer C, Hoevel S, Cal M, Chen G, Zhong L, Katneni K, Pham T, Patil R, Sil D, Walters MJ, Schulze TT, Neville AJ, Dong Y, Wittlin S, Kaiser M, Davis PH, Charman SA, Vennerstrom JL. Ren R, et al. Among authors: leas da. ACS Infect Dis. 2023 Oct 13;9(10):1964-1980. doi: 10.1021/acsinfecdis.3c00245. Epub 2023 Sep 11. ACS Infect Dis. 2023. PMID: 37695781 Free PMC article.
Medium-Ring Keto Bislactams with Antischistosomal Activity.
Ren R, Leas DA, Häberli C, Cal M, Chen G, Katneni K, Dong Y, Kaiser M, Keiser J, Charman SA, Vennerstrom JL. Ren R, et al. Among authors: leas da. J Med Chem. 2024 Oct 24;67(20):18235-18246. doi: 10.1021/acs.jmedchem.4c01532. Epub 2024 Oct 8. J Med Chem. 2024. PMID: 39377659
Single-Dose Drug Development Candidate for Schistosomiasis.
Leas DA, Keiser J, Charman SA, Shackleford DM, Jones JO, Campbell M, Chen G, Katneni K, Patil R, Hu M, Pham T, Häberli C, Schulze TT, Neville AJ, Wang X, Dong Y, Davis PH, Vennerstrom JL. Leas DA, et al. ACS Infect Dis. 2024 Nov 8;10(11):3963-3972. doi: 10.1021/acsinfecdis.4c00677. Epub 2024 Oct 18. ACS Infect Dis. 2024. PMID: 39423362
Synthesis of 2-Azaadamantan-6-one: A Missing Isomer.
Wu J, Leas DA, Dong Y, Wang X, Ezell EL, Stack DE, Vennerstrom JL. Wu J, et al. Among authors: leas da. ACS Omega. 2018 Sep 30;3(9):11362-11367. doi: 10.1021/acsomega.8b01819. Epub 2018 Sep 18. ACS Omega. 2018. PMID: 30288462 Free PMC article.
12 results