Zampella A - Search Results

1

The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.

Biagioli M, Carino A, Fiorucci C, Marchianò S, Di Giorgio C, Bordoni M, Roselli R, Baldoni M, Distrutti E, Zampella A, Fiorucci S. Biagioli M, et al. Among authors: zampella a. J Immunol. 2020 May 1;204(9):2535-2551. doi: 10.4049/jimmunol.1901427. Epub 2020 Mar 25. J Immunol. 2020. PMID: 32213564

2

Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity.

Festa C, De Marino S, D'Auria MV, Bifulco G, Renga B, Fiorucci S, Petek S, Zampella A. Festa C, et al. Among authors: zampella a. J Med Chem. 2011 Jan 13;54(1):401-5. doi: 10.1021/jm100968b. Epub 2010 Dec 9. J Med Chem. 2011. PMID: 21141967

3

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.

Sepe V, Bifulco G, Renga B, D'Amore C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: zampella a. J Med Chem. 2011 Mar 10;54(5):1314-20. doi: 10.1021/jm101336m. Epub 2011 Feb 10. J Med Chem. 2011. PMID: 21309576

4

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

De Marino S, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Fiorucci S, Debitus C, Zampella A. De Marino S, et al. Among authors: zampella a. J Med Chem. 2011 Apr 28;54(8):3065-75. doi: 10.1021/jm200169t. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21428459

5

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei.

De Marino S, Sepe V, D'Auria MV, Bifulco G, Renga B, Petek S, Fiorucci S, Zampella A. De Marino S, et al. Among authors: zampella a. Org Biomol Chem. 2011 Jul 7;9(13):4856-62. doi: 10.1039/c1ob05378g. Epub 2011 May 16. Org Biomol Chem. 2011. PMID: 21584311

6

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Sepe V, Ummarino R, D'Auria MV, Mencarelli A, D'Amore C, Renga B, Zampella A, Fiorucci S. Sepe V, et al. Among authors: zampella a. J Med Chem. 2011 Jul 14;54(13):4590-9. doi: 10.1021/jm200241s. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21599020

7

Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA.

Fiorucci S, Cipriani S, Mencarelli A, Baldelli F, Bifulco G, Zampella A. Fiorucci S, et al. Among authors: zampella a. Mini Rev Med Chem. 2011 Aug;11(9):753-62. doi: 10.2174/138955711796355258. Mini Rev Med Chem. 2011. PMID: 21707532

8

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate.

Renga B, Mencarelli A, Cipriani S, D'Amore C, Zampella A, Monti MC, Distrutti E, Fiorucci S. Renga B, et al. Among authors: zampella a. Biochim Biophys Acta. 2011 Nov;1812(11):1522-31. doi: 10.1016/j.bbadis.2011.06.009. Epub 2011 Jul 1. Biochim Biophys Acta. 2011. PMID: 21757002 Free article.

9

Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

Sepe V, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Debitus C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: zampella a. J Med Chem. 2012 Jan 12;55(1):84-93. doi: 10.1021/jm201004p. Epub 2011 Dec 14. J Med Chem. 2012. PMID: 22126372

10

Quantitative NMR-derived interproton distances combined with quantum mechanical calculations of 13C chemical shifts in the stereochemical determination of conicasterol F, a nuclear receptor ligand from Theonella swinhoei.

Chini MG, Jones CR, Zampella A, D'Auria MV, Renga B, Fiorucci S, Butts CP, Bifulco G. Chini MG, et al. Among authors: zampella a. J Org Chem. 2012 Feb 3;77(3):1489-96. doi: 10.1021/jo2023763. Epub 2012 Jan 23. J Org Chem. 2012. PMID: 22201476

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