Andrei SA - Search Results

1

Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.

Kaplan A, Andrei SA, van Regteren Altena A, Simas T, Banerjee SL, Kato N, Bisson N, Higuchi Y, Ottmann C, Fournier AE. Kaplan A, et al. Among authors: andrei sa. Cell Chem Biol. 2020 Jun 18;27(6):657-667.e6. doi: 10.1016/j.chembiol.2020.02.010. Epub 2020 Mar 26. Cell Chem Biol. 2020. PMID: 32220335 Free article.

2

Designed Spiroketal Protein Modulation.

Scheepstra M, Andrei SA, Unver MY, Hirsch AKH, Leysen S, Ottmann C, Brunsveld L, Milroy LG. Scheepstra M, et al. Among authors: andrei sa. Angew Chem Int Ed Engl. 2017 May 8;56(20):5480-5484. doi: 10.1002/anie.201612504. Epub 2017 Apr 13. Angew Chem Int Ed Engl. 2017. PMID: 28407400 Free PMC article.

3

Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.

Doveston RG, Kuusk A, Andrei SA, Leysen S, Cao Q, Castaldi MP, Hendricks A, Brunsveld L, Chen H, Boyd H, Ottmann C. Doveston RG, et al. Among authors: andrei sa. FEBS Lett. 2017 Aug;591(16):2449-2457. doi: 10.1002/1873-3468.12723. Epub 2017 Aug 6. FEBS Lett. 2017. PMID: 28640363 Free article.

4

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.

Scheepstra M, Andrei SA, de Vries RMJM, Meijer FA, Ma JN, Burstein ES, Olsson R, Ottmann C, Milroy LG, Brunsveld L. Scheepstra M, et al. Among authors: andrei sa. ACS Chem Neurosci. 2017 Sep 20;8(9):2065-2077. doi: 10.1021/acschemneuro.7b00216. Epub 2017 Jul 24. ACS Chem Neurosci. 2017. PMID: 28691794 Free PMC article.

5

Stabilization of protein-protein interactions in drug discovery.

Andrei SA, Sijbesma E, Hann M, Davis J, O'Mahony G, Perry MWD, Karawajczyk A, Eickhoff J, Brunsveld L, Doveston RG, Milroy LG, Ottmann C. Andrei SA, et al. Expert Opin Drug Discov. 2017 Sep;12(9):925-940. doi: 10.1080/17460441.2017.1346608. Epub 2017 Jul 11. Expert Opin Drug Discov. 2017. PMID: 28695752 Free article. Review.

6

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes.

Andrei SA, Meijer FA, Neves JF, Brunsveld L, Landrieu I, Ottmann C, Milroy LG. Andrei SA, et al. ACS Chem Neurosci. 2018 Nov 21;9(11):2639-2654. doi: 10.1021/acschemneuro.8b00118. Epub 2018 May 17. ACS Chem Neurosci. 2018. PMID: 29722962 Free PMC article.

7

Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14-3-3 Protein-Protein Interactions.

Andrei SA, de Vink P, Sijbesma E, Han L, Brunsveld L, Kato N, Ottmann C, Higuchi Y. Andrei SA, et al. Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13470-13474. doi: 10.1002/anie.201806584. Epub 2018 Sep 17. Angew Chem Int Ed Engl. 2018. PMID: 30025189

8

Cooperativity basis for small-molecule stabilization of protein-protein interactions.

de Vink PJ, Andrei SA, Higuchi Y, Ottmann C, Milroy LG, Brunsveld L. de Vink PJ, et al. Among authors: andrei sa. Chem Sci. 2019 Jan 25;10(10):2869-2874. doi: 10.1039/c8sc05242e. eCollection 2019 Mar 14. Chem Sci. 2019. PMID: 30996864 Free PMC article.

9

A study on the effect of synthetic α-to-β³-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins.

Andrei SA , Thijssen V , Brunsveld L , Ottmann C , Milroy LG . Andrei SA , et al. Chem Commun (Camb). 2019 Dec 5;55(98):14809-14812. doi: 10.1039/c9cc07982c. Chem Commun (Camb). 2019. PMID: 31763628

10

Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization.

Bosica F, Andrei SA, Neves JF, Brandt P, Gunnarsson A, Landrieu I, Ottmann C, O'Mahony G. Bosica F, et al. Among authors: andrei sa. Chemistry. 2020 Jun 2;26(31):7131-7139. doi: 10.1002/chem.202001608. Epub 2020 May 11. Chemistry. 2020. PMID: 32255539

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