Kato N - Search Results

1

Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.

Kaplan A, Andrei SA, van Regteren Altena A, Simas T, Banerjee SL, Kato N, Bisson N, Higuchi Y, Ottmann C, Fournier AE. Kaplan A, et al. Among authors: kato n. Cell Chem Biol. 2020 Jun 18;27(6):657-667.e6. doi: 10.1016/j.chembiol.2020.02.010. Epub 2020 Mar 26. Cell Chem Biol. 2020. PMID: 32220335 Free article.

2

Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.

Bier D, Bartel M, Sies K, Halbach S, Higuchi Y, Haranosono Y, Brummer T, Kato N, Ottmann C. Bier D, et al. Among authors: kato n. ChemMedChem. 2016 Apr 19;11(8):911-8. doi: 10.1002/cmdc.201500484. Epub 2015 Dec 8. ChemMedChem. 2016. PMID: 26644359

3

Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14-3-3 Protein-Protein Interactions.

Andrei SA, de Vink P, Sijbesma E, Han L, Brunsveld L, Kato N, Ottmann C, Higuchi Y. Andrei SA, et al. Among authors: kato n. Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13470-13474. doi: 10.1002/anie.201806584. Epub 2018 Sep 17. Angew Chem Int Ed Engl. 2018. PMID: 30025189

4

Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products.

Wolter M, de Vink P, Neves JF, Srdanović S, Higuchi Y, Kato N, Wilson A, Landrieu I, Brunsveld L, Ottmann C. Wolter M, et al. Among authors: kato n. J Am Chem Soc. 2020 Jul 8;142(27):11772-11783. doi: 10.1021/jacs.0c02151. Epub 2020 Jun 23. J Am Chem Soc. 2020. PMID: 32501683 Free PMC article.

5

A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.

Anders C, Higuchi Y, Koschinsky K, Bartel M, Schumacher B, Thiel P, Nitta H, Preisig-Müller R, Schlichthörl G, Renigunta V, Ohkanda J, Daut J, Kato N, Ottmann C. Anders C, et al. Among authors: kato n. Chem Biol. 2013 Apr 18;20(4):583-93. doi: 10.1016/j.chembiol.2013.03.015. Chem Biol. 2013. PMID: 23601647

6

Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A.

Inoue T, Higuchi Y, Yoneyama T, Lin B, Nunomura K, Honma Y, Kato N. Inoue T, et al. Among authors: kato n. Bioorg Med Chem Lett. 2018 Feb 15;28(4):646-650. doi: 10.1016/j.bmcl.2018.01.030. Bioorg Med Chem Lett. 2018. PMID: 29398541

7

A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A.

Ottmann C, Weyand M, Sassa T, Inoue T, Kato N, Wittinghofer A, Oecking C. Ottmann C, et al. Among authors: kato n. J Mol Biol. 2009 Mar 6;386(4):913-9. doi: 10.1016/j.jmb.2009.01.005. J Mol Biol. 2009. PMID: 19244612

8

Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells.

Kasukabe T, Honma Y, Okabe-Kado J, Higuchi Y, Kato N, Kumakura S. Kasukabe T, et al. Among authors: kato n. Oncol Rep. 2016 Aug;36(2):968-76. doi: 10.3892/or.2016.4867. Epub 2016 Jun 10. Oncol Rep. 2016. PMID: 27375275

9

Dioxygenases, key enzymes to determine the aglycon structures of fusicoccin and brassicicene, diterpene compounds produced by fungi.

Ono Y, Minami A, Noike M, Higuchi Y, Toyomasu T, Sassa T, Kato N, Dairi T. Ono Y, et al. Among authors: kato n. J Am Chem Soc. 2011 Mar 2;133(8):2548-55. doi: 10.1021/ja107785u. Epub 2011 Feb 7. J Am Chem Soc. 2011. PMID: 21299202

10

Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers.

Molzan M, Kasper S, Röglin L, Skwarczynska M, Sassa T, Inoue T, Breitenbuecher F, Ohkanda J, Kato N, Schuler M, Ottmann C. Molzan M, et al. Among authors: kato n. ACS Chem Biol. 2013 Sep 20;8(9):1869-75. doi: 10.1021/cb4003464. Epub 2013 Jul 5. ACS Chem Biol. 2013. PMID: 23808890

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