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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Kramer J, et al. Among authors: polonchuk l. Sci Rep. 2020 Mar 27;10(1):5627. doi: 10.1038/s41598-020-62344-w. Sci Rep. 2020. PMID: 32221320 Free PMC article.
Human ex-vivo action potential model for pro-arrhythmia risk assessment.
Page G, Ratchada P, Miron Y, Steiner G, Ghetti A, Miller PE, Reynolds JA, Wang K, Greiter-Wilke A, Polonchuk L, Traebert M, Gintant GA, Abi-Gerges N. Page G, et al. Among authors: polonchuk l. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:183-95. doi: 10.1016/j.vascn.2016.05.016. Epub 2016 May 25. J Pharmacol Toxicol Methods. 2016. PMID: 27235787 Free PMC article.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Ridder BJ, Leishman DJ, Bridgland-Taylor M, Samieegohar M, Han X, Wu WW, Randolph A, Tran P, Sheng J, Danker T, Lindqvist A, Konrad D, Hebeisen S, Polonchuk L, Gissinger E, Renganathan M, Koci B, Wei H, Fan J, Levesque P, Kwagh J, Imredy J, Zhai J, Rogers M, Humphries E, Kirby R, Stoelzle-Feix S, Brinkwirth N, Rotordam MG, Becker N, Friis S, Rapedius M, Goetze TA, Strassmaier T, Okeyo G, Kramer J, Kuryshev Y, Wu C, Himmel H, Mirams GR, Strauss DG, Bardenet R, Li Z. Ridder BJ, et al. Among authors: polonchuk l. Toxicol Appl Pharmacol. 2020 May 1;394:114961. doi: 10.1016/j.taap.2020.114961. Epub 2020 Mar 21. Toxicol Appl Pharmacol. 2020. PMID: 32209365 Free PMC article.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Ridder BJ, Leishman DJ, Bridgland-Taylor M, Samieegohar M, Han X, Wu WW, Randolph A, Tran P, Sheng J, Danker T, Lindqvist A, Konrad D, Hebeisen S, Polonchuk L, Gissinger E, Renganathan M, Koci B, Wei H, Fan J, Levesque P, Kwagh J, Imredy J, Zhai J, Rogers M, Humphries E, Kirby R, Stoelzle-Feix S, Brinkwirth N, Rotordam MG, Becker N, Friis S, Rapedius M, Goetze TA, Strassmaier T, Okeyo G, Kramer J, Kuryshev Y, Wu C, Himmel H, Mirams GR, Strauss DG, Bardenet R, Li Z. Ridder BJ, et al. Among authors: polonchuk l. Toxicol Appl Pharmacol. 2020 May 15;395:114983. doi: 10.1016/j.taap.2020.114983. Epub 2020 Apr 2. Toxicol Appl Pharmacol. 2020. PMID: 32247767 Free PMC article. No abstract available.
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Kramer J, et al. Among authors: polonchuk l. Sci Rep. 2020 Jul 14;10(1):11884. doi: 10.1038/s41598-020-68819-0. Sci Rep. 2020. PMID: 32665705 Free PMC article.
Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk.
Davies MR, Martinec M, Walls R, Schwarz R, Mirams GR, Wang K, Steiner G, Surinach A, Flores C, Lavé T, Singer T, Polonchuk L. Davies MR, et al. Among authors: polonchuk l. Cell Rep Med. 2020 Aug 25;1(5):100076. doi: 10.1016/j.xcrm.2020.100076. eCollection 2020 Aug 25. Cell Rep Med. 2020. PMID: 33205069 Free PMC article.
35 results