Bruning JB - Search Results

1

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes.

Coleman T, Stok JE, Podgorski MN, Bruning JB, De Voss JJ, Bell SG. Coleman T, et al. Among authors: bruning jb. J Biol Inorg Chem. 2020 Jun;25(4):583-596. doi: 10.1007/s00775-020-01781-4. Epub 2020 Apr 4. J Biol Inorg Chem. 2020. PMID: 32248305

2

Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from Mycobacterium marinum.

Child SA, Naumann EF, Bruning JB, Bell SG. Child SA, et al. Among authors: bruning jb. Biochem J. 2018 Feb 16;475(4):705-722. doi: 10.1042/BCJ20170946. Biochem J. 2018. PMID: 29343612

3

The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum.

Child SA, Flint KL, Bruning JB, Bell SG. Child SA, et al. Among authors: bruning jb. Biochim Biophys Acta Gen Subj. 2019 May;1863(5):925-934. doi: 10.1016/j.bbagen.2019.02.016. Epub 2019 Feb 28. Biochim Biophys Acta Gen Subj. 2019. PMID: 30826435

4

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions.

Podgorski MN, Coleman T, Chao RR, De Voss JJ, Bruning JB, Bell SG. Podgorski MN, et al. Among authors: bruning jb. J Inorg Biochem. 2020 Feb;203:110913. doi: 10.1016/j.jinorgbio.2019.110913. Epub 2019 Nov 13. J Inorg Biochem. 2020. PMID: 31759265

5

Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases.

Podgorski MN, Harbort JS, Coleman T, Stok JE, Yorke JA, Wong LL, Bruning JB, Bernhardt PV, De Voss JJ, Harmer JR, Bell SG. Podgorski MN, et al. Among authors: bruning jb. Biochemistry. 2020 Mar 10;59(9):1038-1050. doi: 10.1021/acs.biochem.0c00027. Epub 2020 Feb 24. Biochemistry. 2020. PMID: 32058707

6

d-Alanine-d-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations.

Pederick JL, Thompson AP, Bell SG, Bruning JB. Pederick JL, et al. Among authors: bruning jb. J Biol Chem. 2020 Jun 5;295(23):7894-7904. doi: 10.1074/jbc.RA120.012936. Epub 2020 Apr 25. J Biol Chem. 2020. PMID: 32335509 Free PMC article.

7

A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis.

Child SA, Ghith A, Bruning JB, Bell SG. Child SA, et al. Among authors: bruning jb. J Inorg Biochem. 2020 Aug;209:111116. doi: 10.1016/j.jinorgbio.2020.111116. Epub 2020 May 20. J Inorg Biochem. 2020. PMID: 32473484

8

The Stereoselective Oxidation of para-Substituted Benzenes by a Cytochrome P450 Biocatalyst.

Chao RR, Lau IC, Coleman T, Churchman LR, Child SA, Lee JHZ, Bruning JB, De Voss JJ, Bell SG. Chao RR, et al. Among authors: bruning jb. Chemistry. 2021 Oct 21;27(59):14765-14777. doi: 10.1002/chem.202102757. Epub 2021 Sep 12. Chemistry. 2021. PMID: 34350662

9

To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme.

Podgorski MN, Coleman T, Giang PD, Wang CR, Bruning JB, Bernhardt PV, De Voss JJ, Bell SG. Podgorski MN, et al. Among authors: bruning jb. Inorg Chem. 2022 Jan 10;61(1):236-245. doi: 10.1021/acs.inorgchem.1c02786. Epub 2021 Dec 15. Inorg Chem. 2022. PMID: 34910500

10

A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis.

Mohamed H, Child SA, Bruning JB, Bell SG. Mohamed H, et al. Among authors: bruning jb. J Steroid Biochem Mol Biol. 2022 Jul;221:106097. doi: 10.1016/j.jsbmb.2022.106097. Epub 2022 Mar 25. J Steroid Biochem Mol Biol. 2022. PMID: 35346833

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