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Prenylated Curcumin Analogues as Multipotent Tools To Tackle Alzheimer's Disease.
Bisceglia F, Seghetti F, Serra M, Zusso M, Gervasoni S, Verga L, Vistoli G, Lanni C, Catanzaro M, De Lorenzi E, Belluti F. Bisceglia F, et al. Among authors: seghetti f. ACS Chem Neurosci. 2019 Mar 20;10(3):1420-1433. doi: 10.1021/acschemneuro.8b00463. Epub 2019 Jan 2. ACS Chem Neurosci. 2019. PMID: 30556996 Free article.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.
Di Martino RMC, Pruccoli L, Bisi A, Gobbi S, Rampa A, Martinez A, Pérez C, Martinez-Gonzalez L, Paglione M, Di Schiavi E, Seghetti F, Tarozzi A, Belluti F. Di Martino RMC, et al. Among authors: seghetti f. ACS Chem Neurosci. 2020 Sep 2;11(17):2728-2740. doi: 10.1021/acschemneuro.0c00363. Epub 2020 Aug 3. ACS Chem Neurosci. 2020. PMID: 32663009 Free PMC article.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.
De Lorenzi E, Seghetti F, Tarozzi A, Pruccoli L, Contardi C, Serra M, Bisi A, Gobbi S, Vistoli G, Gervasoni S, Argentini C, Ghirardo G, Guarato G, Orso G, Belluti F, Di Martino RMC, Zusso M. De Lorenzi E, et al. Among authors: seghetti f. Eur J Med Chem. 2023 Apr 5;252:115297. doi: 10.1016/j.ejmech.2023.115297. Epub 2023 Mar 21. Eur J Med Chem. 2023. PMID: 36996713 Free article.
The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
de Freitas Silva M, Pruccoli L, Morroni F, Sita G, Seghetti F, Viegas C, Tarozzi A. de Freitas Silva M, et al. Among authors: seghetti f. Molecules. 2018 Jul 20;23(7):1803. doi: 10.3390/molecules23071803. Molecules. 2018. PMID: 30037040 Free PMC article. Review.
15 results