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Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.
Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, Fukase Y, Aso K, Foley MA, Gelfand VI, Chen JK, Carter AP, Kapoor TM. Steinman JB, et al. Among authors: ondrus ae. Elife. 2017 May 19;6:e25174. doi: 10.7554/eLife.25174. Elife. 2017. PMID: 28524820 Free PMC article.
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1.
Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernández D, Ondrus AE, Gu Y, McCormick AK, Tomaske MG, Marshall CR, Kline T, Chen CH, Mochly-Rosen D, Kuo CJ, Chen JK. Feng Z, et al. Among authors: ondrus ae. Nat Chem Biol. 2022 Oct;18(10):1065-1075. doi: 10.1038/s41589-022-01048-w. Epub 2022 Jul 4. Nat Chem Biol. 2022. PMID: 35788181 Free PMC article.
Author Correction: Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1.
Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernández D, Ondrus AE, Gu Y, McCormick AK, Tomaske MG, Marshall CR, Kline T, Chen CH, Mochly-Rosen D, Kuo CJ, Chen JK. Feng Z, et al. Among authors: ondrus ae. Nat Chem Biol. 2024 Dec 9. doi: 10.1038/s41589-024-01810-2. Online ahead of print. Nat Chem Biol. 2024. PMID: 39653787 No abstract available.
Indolactam Dipeptides as Nanomolar Gli Inhibitors.
Mendoza M, Tran U, Zhang GC, Leister J, To K, Malepeai-Tofaeono T, Ondrus AE, Billingsley KL. Mendoza M, et al. Among authors: ondrus ae. ACS Med Chem Lett. 2022 Jun 3;13(7):1036-1042. doi: 10.1021/acsmedchemlett.1c00562. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859880 Free PMC article.
Total synthesis and study of myrmicarin alkaloids.
Ondrus AE, Movassaghi M. Ondrus AE, et al. Chem Commun (Camb). 2009 Jul 28;(28):4151-65. doi: 10.1039/b903995n. Epub 2009 May 19. Chem Commun (Camb). 2009. PMID: 19585010 Free PMC article.
23 results