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Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice.
Stein M, Barnea-Zohar M, Shalev M, Arman E, Brenner O, Winograd-Katz S, Gerstung J, Thalji F, Kanaan M, Elinav H, Stepensky P, Geiger B, Tuckermann J, Elson A. Stein M, et al. Among authors: tuckermann j. Bone. 2020 Jul;136:115360. doi: 10.1016/j.bone.2020.115360. Epub 2020 Apr 8. Bone. 2020. PMID: 32278070
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.
Barnea-Zohar M, Winograd-Katz SE, Shalev M, Arman E, Reuven N, Roth L, Golani O, Stein M, Thalji F, Kanaan M, Tuckermann J, Geiger B, Elson A. Barnea-Zohar M, et al. Among authors: tuckermann j. J Cell Sci. 2021 May 1;134(9):jcs254979. doi: 10.1242/jcs.254979. Epub 2021 May 11. J Cell Sci. 2021. PMID: 33975343 Free PMC article.
Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling.
Bartelt A, Behler-Janbeck F, Beil FT, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann JP, Amling M, Herz J, Schinke T, Heeren J, Niemeier A. Bartelt A, et al. Among authors: tuckermann jp. Bone Res. 2018 Feb 26;6:4. doi: 10.1038/s41413-017-0006-3. eCollection 2018. Bone Res. 2018. PMID: 29507818 Free PMC article.
193 results