Lamb DJ - Search Results

1

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells.

Lamb DJ, Rust A, Rudisch A, Glüxam T, Harrer N, Machat H, Christ I, Colbatzky F, Wernitznig A, Osswald A, Sommergruber W. Lamb DJ, et al. Oncotarget. 2020 Apr 7;11(14):1257-1272. doi: 10.18632/oncotarget.27545. eCollection 2020 Apr 7. Oncotarget. 2020. PMID: 32292575 Free PMC article.

2

Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.

Gindele JA, Mang S, Pairet N, Christ I, Gantner F, Schymeinsky J, Lamb DJ. Gindele JA, et al. Among authors: lamb dj. PLoS One. 2017 Sep 1;12(9):e0184386. doi: 10.1371/journal.pone.0184386. eCollection 2017. PLoS One. 2017. PMID: 28863189 Free PMC article.

3

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.

Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M. Lamb DJ, et al. J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5. J Pharmacol Exp Ther. 2016. PMID: 27048659

4

Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.

Tabeling C, Herbert J, Hocke AC, Lamb DJ, Wollin SL, Erb KJ, Boiarina E, Movassagh H, Scheffel J, Doehn JM, Hippenstiel S, Maurer M, Gounni AS, Kuebler WM, Suttorp N, Witzenrath M. Tabeling C, et al. Among authors: lamb dj. Allergy. 2017 Jul;72(7):1061-1072. doi: 10.1111/all.13101. Epub 2017 Jan 12. Allergy. 2017. PMID: 27906453

5

Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice.

Bucher H, Mang S, Keck M, Przibilla M, Lamb DJ, Schiele F, Wittenbrink M, Fuchs K, Jung B, Erb KJ, Peter D. Bucher H, et al. Among authors: lamb dj. Pulm Pharmacol Ther. 2017 Jun;44:96-105. doi: 10.1016/j.pupt.2017.03.008. Epub 2017 Mar 15. Pulm Pharmacol Ther. 2017. PMID: 28315490 Free article.

6

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction.

van Eeuwijk JM, Stegner D, Lamb DJ, Kraft P, Beck S, Thielmann I, Kiefer F, Walzog B, Stoll G, Nieswandt B. van Eeuwijk JM, et al. Among authors: lamb dj. Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1247-53. doi: 10.1161/ATVBAHA.115.306883. Epub 2016 Apr 21. Arterioscler Thromb Vasc Biol. 2016. PMID: 27102960

7

Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis.

Pairet N, Mang S, Kiechle T, Laufhäger N, Dietl P, Lamb DJ. Pairet N, et al. Among authors: lamb dj. Biochem Biophys Rep. 2019 Sep 19;20:100672. doi: 10.1016/j.bbrep.2019.100672. eCollection 2019 Dec. Biochem Biophys Rep. 2019. PMID: 31650038 Free PMC article.

8

RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma.

Lamb D, De Sousa D, Quast K, Fundel-Clemens K, Erjefält JS, Sandén C, Hoffmann HJ, Kästle M, Schmid R, Menden K, Delic D. Lamb D, et al. Respir Res. 2021 May 22;22(1):158. doi: 10.1186/s12931-021-01743-7. Respir Res. 2021. PMID: 34022896 Free PMC article.

9

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation.

Pairet N, Mang S, Fois G, Keck M, Kühnbach M, Gindele J, Frick M, Dietl P, Lamb DJ. Pairet N, et al. Among authors: lamb dj. PLoS One. 2018 Apr 17;13(4):e0196055. doi: 10.1371/journal.pone.0196055. eCollection 2018. PLoS One. 2018. PMID: 29664963 Free PMC article.

10

Characterization of a flexible AAV-DTR/DT mouse model of acute epithelial lung injury.

Griesser E, Schönberger T, Stierstorfer B, Wyatt H, Rist W, Lamla T, Thomas MJ, Lamb D, Geillinger-Kästle K. Griesser E, et al. Am J Physiol Lung Cell Mol Physiol. 2022 Aug 1;323(2):L206-L218. doi: 10.1152/ajplung.00364.2021. Epub 2022 Jun 28. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35762632 Free article.

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