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Cell-permeable lanthanide-platinum(IV) anti-cancer prodrugs.
Yao K, Karunanithy G, Howarth A, Holdship P, Thompson AL, Christensen KE, Baldwin AJ, Faulkner S, Farrer NJ. Yao K, et al. Among authors: howarth a. Dalton Trans. 2021 Jun 29;50(25):8761-8767. doi: 10.1039/d1dt01688a. Dalton Trans. 2021. PMID: 34080595 Free PMC article.
A visible-light photoactivatable di-nuclear PtIV triazolato azido complex.
Yao K , Bertran A , Howarth A , Goicoechea JM , Hare SM , Rees NH , Foroozandeh M , Bowen AM , Farrer NJ . Yao K , et al. Among authors: howarth a. Chem Commun (Camb). 2019 Sep 17;55(75):11287-11290. doi: 10.1039/c9cc05310g. Chem Commun (Camb). 2019. PMID: 31475995 Free PMC article.
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma.
Smil D, Wong JF, Williams EP, Adamson RJ, Howarth A, McLeod DA, Mamai A, Kim S, Wilson BJ, Kiyota T, Aman A, Owen J, Poda G, Horiuchi KY, Kuznetsova E, Ma H, Hamblin JN, Cramp S, Roberts OG, Edwards AM, Uehling D, Al-Awar R, Bullock AN, O'Meara JA, Isaac MB. Smil D, et al. Among authors: howarth a. J Med Chem. 2020 Sep 10;63(17):10061-10085. doi: 10.1021/acs.jmedchem.0c01199. Epub 2020 Aug 26. J Med Chem. 2020. PMID: 32787083 Free article.
SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection.
Wei J, Matthews PC, Stoesser N, Diamond I, Studley R, Rourke E, Cook D, Bell JI, Newton JN, Farrar J, Howarth A, Marsden BD, Hoosdally S, Jones EY, Stuart DI, Crook DW, Peto TEA, Walker AS, Eyre DW, Pouwels KB; COVID-19 Infection Survey team. Wei J, et al. Among authors: howarth a. Nat Commun. 2022 Jun 29;13(1):3748. doi: 10.1038/s41467-022-31495-x. Nat Commun. 2022. PMID: 35768431 Free PMC article.
BET inhibition as a new strategy for the treatment of gastric cancer.
Montenegro RC, Clark PG, Howarth A, Wan X, Ceroni A, Siejka P, Nunez-Alonso GA, Monteiro O, Rogers C, Gamble V, Burbano R, Brennan PE, Tallant C, Ebner D, Fedorov O, O'Neill E, Knapp S, Dixon D, Müller S. Montenegro RC, et al. Among authors: howarth a. Oncotarget. 2016 Jul 12;7(28):43997-44012. doi: 10.18632/oncotarget.9766. Oncotarget. 2016. PMID: 27259267 Free PMC article.
Tracking the Emergence of SARS-CoV-2 Alpha Variant in the United Kingdom.
Walker AS, Vihta KD, Gethings O, Pritchard E, Jones J, House T, Bell I, Bell JI, Newton JN, Farrar J, Diamond I, Studley R, Rourke E, Hay J, Hopkins S, Crook D, Peto T, Matthews PC, Eyre DW, Stoesser N, Pouwels KB; Covid-19 Infection Survey Team. Walker AS, et al. N Engl J Med. 2021 Dec 30;385(27):2582-2585. doi: 10.1056/NEJMc2103227. Epub 2021 Dec 8. N Engl J Med. 2021. PMID: 34879193 Free PMC article. No abstract available.
Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers.
Lumley SF, O'Donnell D, Stoesser NE, Matthews PC, Howarth A, Hatch SB, Marsden BD, Cox S, James T, Warren F, Peck LJ, Ritter TG, de Toledo Z, Warren L, Axten D, Cornall RJ, Jones EY, Stuart DI, Screaton G, Ebner D, Hoosdally S, Chand M, Crook DW, O'Donnell AM, Conlon CP, Pouwels KB, Walker AS, Peto TEA, Hopkins S, Walker TM, Jeffery K, Eyre DW; Oxford University Hospitals Staff Testing Group. Lumley SF, et al. Among authors: howarth a. N Engl J Med. 2021 Feb 11;384(6):533-540. doi: 10.1056/NEJMoa2034545. Epub 2020 Dec 23. N Engl J Med. 2021. PMID: 33369366 Free PMC article.
The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers.
Lumley SF, Wei J, O'Donnell D, Stoesser NE, Matthews PC, Howarth A, Hatch SB, Marsden BD, Cox S, James T, Peck LJ, Ritter TG, de Toledo Z, Cornall RJ, Jones EY, Stuart DI, Screaton G, Ebner D, Hoosdally S, Crook DW, Conlon CP, Pouwels KB, Walker AS, Peto TEA, Walker TM, Jeffery K, Eyre DW; Oxford University Hospitals Staff Testing Group. Lumley SF, et al. Among authors: howarth a. Clin Infect Dis. 2021 Aug 2;73(3):e699-e709. doi: 10.1093/cid/ciab004. Clin Infect Dis. 2021. PMID: 33400782 Free PMC article.
279 results