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214 results

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Page 1
Structural heart transcatheter interventions in orthotopic cardiac transplant and left ventricular assist devices recipients: A nationwide study.
Blasco-Turrión S, Crespo-Leiro MG, Donoso Trenado V, Chi Hion PL, Díaz Molina B, Roura G, Álvarez-Osorio MP, Gómez-Bueno M, Ortiz Bautista C, Diaz JF, Garrido Bravo IP, Moreno R, Sarnago-Cebada F, Salterain González N, de la Torre Hernandez JM, García Del Blanco B, Farrero M, Ortas Nadal R, Martin P, de La Fuente L, Sanz-Sánchez J, Mirabet Pérez S, Alonso Fernández V, Gómez Hospital JA, López Granados A, Couto-Mallon D, Del Trigo Espinosa M, Rangel Sousa D, Zatarain-Nicolás E, Arzamendi Aizpurua D, López Vilella R, San Román JA, Amat-Santos IJ. Blasco-Turrión S, et al. Among authors: diaz jf. Int J Cardiol. 2024 Oct 15;413:132340. doi: 10.1016/j.ijcard.2024.132340. Epub 2024 Jul 9. Int J Cardiol. 2024. PMID: 38992809
Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.
Kalnins T, Vitkovska V, Kazak M, Zelencova-Gopejenko D, Ozola M, Narvaiss N, Makrecka-Kuka M, Domračeva I, Kinens A, Gukalova B, Konrad N, Aav R, Bonato F, Lucena-Agell D, Díaz JF, Liepinsh E, Suna E. Kalnins T, et al. Among authors: diaz jf. J Med Chem. 2024 Jun 13;67(11):9227-9259. doi: 10.1021/acs.jmedchem.4c00388. Epub 2024 Jun 4. J Med Chem. 2024. PMID: 38833507
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF. Lucena-Agell D, et al. Among authors: diaz jf. J Med Chem. 2024 Feb 22;67(4):2619-2630. doi: 10.1021/acs.jmedchem.3c01775. Epub 2024 Jan 31. J Med Chem. 2024. PMID: 38294341 Free PMC article.
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Ma Y, Josa-Prado F, Essif JN, Liu S, Li S, Lucena-Agell D, Chan PY, Goossens K, Hortigüela R, Matesanz R, Wang Y, Gago F, Wang H, Risinger A, Diaz JF, Fang WS. Ma Y, et al. Among authors: diaz jf. Eur J Med Chem. 2023 Nov 5;259:115668. doi: 10.1016/j.ejmech.2023.115668. Epub 2023 Jul 19. Eur J Med Chem. 2023. PMID: 37490800
214 results