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A Randomized Dose-Escalating Phase I Trial of a Replication-Deficient Lymphocytic Choriomeningitis Virus Vector-Based Vaccine Against Human Cytomegalovirus.
Schwendinger M, Thiry G, De Vos B, Leroux-Roels G, Bruhwyler J, Huygens A, Ganeff C, Buchinger H, Orlinger KK, Pinschewer DD, Monath TP, Lilja AE. Schwendinger M, et al. Among authors: pinschewer dd. J Infect Dis. 2022 Apr 19;225(8):1399-1410. doi: 10.1093/infdis/jiaa121. J Infect Dis. 2022. PMID: 32313928 Free PMC article. Clinical Trial.
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, Pinschewer DD. Marx AF, et al. Among authors: pinschewer dd. Immunity. 2023 Apr 11;56(4):813-828.e10. doi: 10.1016/j.immuni.2023.01.029. Epub 2023 Feb 20. Immunity. 2023. PMID: 36809763 Free article.
Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector.
Schleiss MR, Berka U, Watson E, Aistleithner M, Kiefmann B, Mangeat B, Swanson EC, Gillis PA, Hernandez-Alvarado N, Fernández-Alarcón C, Zabeli JC, Pinschewer DD, Lilja AE, Schwendinger M, Guirakhoo F, Monath TP, Orlinger KK. Schleiss MR, et al. Among authors: pinschewer dd. Clin Vaccine Immunol. 2017 Jan 5;24(1):e00300-16. doi: 10.1128/CVI.00300-16. Print 2017 Jan. Clin Vaccine Immunol. 2017. PMID: 27795301 Free PMC article.
Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.
Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH. Penaloza MacMaster P, et al. Among authors: pinschewer dd. Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26. Vaccine. 2017. PMID: 27899229 Free PMC article.
Live-attenuated lymphocytic choriomeningitis virus-based vaccines for active immunotherapy of HPV16-positive cancer.
Schmidt S, Bonilla WV, Reiter A, Stemeseder F, Kleissner T, Oeler D, Berka U, El-Gazzar A, Kiefmann B, Schulha SC, Raguz J, Habbeddine M, Scheinost M, Qing X, Lauterbach H, Matushansky I, Pinschewer DD, Orlinger KK. Schmidt S, et al. Among authors: pinschewer dd. Oncoimmunology. 2020 Sep 15;9(1):1809960. doi: 10.1080/2162402X.2020.1809960. Oncoimmunology. 2020. PMID: 33457095 Free PMC article.
Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack.
Bonilla WV, Kirchhammer N, Marx AF, Kallert SM, Krzyzaniak MA, Lu M, Darbre S, Schmidt S, Raguz J, Berka U, Vincenti I, Pauzuolis M, Kerber R, Hoepner S, Günther S, Magnus C, Merkler D, Orlinger KK, Zippelius A, Pinschewer DD. Bonilla WV, et al. Among authors: pinschewer dd. Cell Rep Med. 2021 Mar 3;2(3):100209. doi: 10.1016/j.xcrm.2021.100209. eCollection 2021 Mar 16. Cell Rep Med. 2021. PMID: 33763654 Free PMC article.
Development and Characterization of a Novel Non-Lytic Cancer Immunotherapy Using a Recombinant Arenavirus Vector Platform.
Lauterbach H, Schmidt S, Katchar K, Qing X, Iacobucci C, Hwang A, Schlienger K, Berka U, Raguz J, Ahmadi-Erber S, Schippers T, Stemeseder F, Pinschewer DD, Matushansky I, Orlinger KK. Lauterbach H, et al. Among authors: pinschewer dd. Front Oncol. 2021 Oct 14;11:732166. doi: 10.3389/fonc.2021.732166. eCollection 2021. Front Oncol. 2021. PMID: 34722273 Free PMC article. Review.
92 results