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Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
Richter K, Rufer AC, Muller M, Burger D, Casagrande F, Grossenbacher T, Huber S, Hug MN, Koldewey P, D'Osualdo A, Schlatter D, Stoll T, Rudolph MG. Richter K, et al. Among authors: koldewey p. J Biol Chem. 2020 Jun 5;295(23):7849-7864. doi: 10.1074/jbc.RA120.012788. Epub 2020 Apr 21. J Biol Chem. 2020. PMID: 32317279 Free PMC article.
Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1.
Richter K, Rufer AC, Muller M, Burger D, Casagrande F, Grossenbacher T, Huber S, Hug MN, Koldewey P, D'Osualdo A, Schlatter D, Stoll T, Rudolph MG. Richter K, et al. Among authors: koldewey p. J Biol Chem. 2020 Jul 17;295(29):10077. doi: 10.1074/jbc.RL120.014441. J Biol Chem. 2020. PMID: 32680972 Free PMC article. No abstract available.
Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.
Obst-Sander U, Ricci A, Kuhn B, Friess T, Koldewey P, Kuglstatter A, Hewings D, Goergler A, Steiner S, Rueher D, Imhoff MP, Raschetti N, Marty HP, Dietzig A, Rynn C, Ehler A, Burger D, Kornacker M, Schaffland JP, Herting F, Pao W, Bischoff JR, Martoglio B, Alice Nagel Y, Jaeschke G. Obst-Sander U, et al. Among authors: koldewey p. J Med Chem. 2022 Oct 13;65(19):13052-13073. doi: 10.1021/acs.jmedchem.2c00893. Epub 2022 Sep 30. J Med Chem. 2022. PMID: 36178776
HdeB functions as an acid-protective chaperone in bacteria.
Dahl JU, Koldewey P, Salmon L, Horowitz S, Bardwell JC, Jakob U. Dahl JU, et al. Among authors: koldewey p. J Biol Chem. 2015 Jan 2;290(1):65-75. doi: 10.1074/jbc.M114.612986. Epub 2014 Nov 12. J Biol Chem. 2015. PMID: 25391835 Free PMC article.
HdeB functions as an acid-protective chaperone in bacteria.
Dahl JU, Koldewey P, Salmon L, Horowitz S, Bardwell JC, Jakob U. Dahl JU, et al. Among authors: koldewey p. J Biol Chem. 2015 Apr 17;290(16):9950. doi: 10.1074/jbc.A114.612986. J Biol Chem. 2015. PMID: 25888567 Free PMC article. No abstract available.
23 results