Rationally designed anti-HIV peptides containing multifunctional domains as molecule probes for studying the mechanisms of action of the first and second generation HIV fusion inhibitors.
Qi Z, Shi W, Xue N, Pan C, Jing W, Liu K, Jiang S.
Qi Z, et al. Among authors: jiang s.
J Biol Chem. 2008 Oct 31;283(44):30376-84. doi: 10.1074/jbc.M804672200. Epub 2008 Jul 28.
J Biol Chem. 2008.
PMID: 18662985
Free PMC article.
We have previously shown that the first generation human immunodeficiency virus (HIV) fusion inhibitor T20 (Fuzeon) contains a critical lipid-binding domain (LBD), whereas C34, another anti-HIV peptide derived from the gp41 C-terminal heptad repeat, consists of an important pocke …
We have previously shown that the first generation human immunodeficiency virus (HIV) fusion inhibitor T20 (Fuzeon) contains a critical lipi …