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MicroRNA-483 amelioration of experimental pulmonary hypertension.
Zhang J, He Y, Yan X, Chen S, He M, Lei Y, Zhang J, Gongol B, Gu M, Miao Y, Bai L, Cui X, Wang X, Zhang Y, Fan F, Li Z, Shen Y, Chou CH, Huang HD, Malhotra A, Rabinovitch M, Jing ZC, Shyy JY. Zhang J, et al. Among authors: rabinovitch m. EMBO Mol Med. 2020 May 8;12(5):e11303. doi: 10.15252/emmm.201911303. Epub 2020 Apr 23. EMBO Mol Med. 2020. PMID: 32324970 Free PMC article.
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension.
Merklinger SL, Wagner RA, Spiekerkoetter E, Hinek A, Knutsen RH, Kabir MG, Desai K, Hacker S, Wang L, Cann GM, Ambartsumian NS, Lukanidin E, Bernstein D, Husain M, Mecham RP, Starcher B, Yanagisawa H, Rabinovitch M. Merklinger SL, et al. Among authors: rabinovitch m. Circ Res. 2005 Sep 16;97(6):596-604. doi: 10.1161/01.RES.0000182425.49768.8a. Epub 2005 Aug 18. Circ Res. 2005. PMID: 16109920
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.
Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, Bernstein D, Solow-Cordero DE, Beachy PA, Wandless TJ, Ten Dijke P, Rabinovitch M. Spiekerkoetter E, et al. Among authors: rabinovitch m. J Clin Invest. 2013 Aug;123(8):3600-13. doi: 10.1172/JCI65592. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867624 Free PMC article.
Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
Sawada H, Saito T, Nickel NP, Alastalo TP, Glotzbach JP, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai YJ, Perez Vde J, Kim YM, Wang L, Chen PI, Spiekerkoetter E, Mitani Y, Gurtner GC, Sarnow P, Rabinovitch M. Sawada H, et al. Among authors: rabinovitch m. J Exp Med. 2014 Feb 10;211(2):263-80. doi: 10.1084/jem.20111741. Epub 2014 Jan 20. J Exp Med. 2014. PMID: 24446489 Free PMC article.
Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.
Nickel NP, Spiekerkoetter E, Gu M, Li CG, Li H, Kaschwich M, Diebold I, Hennigs JK, Kim KY, Miyagawa K, Wang L, Cao A, Sa S, Jiang X, Stockstill RW, Nicolls MR, Zamanian RT, Bland RD, Rabinovitch M. Nickel NP, et al. Among authors: rabinovitch m. Am J Respir Crit Care Med. 2015 Jun 1;191(11):1273-86. doi: 10.1164/rccm.201412-2291OC. Am J Respir Crit Care Med. 2015. PMID: 25853696 Free PMC article.
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.
Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M. Diebold I, et al. Among authors: rabinovitch m. Cell Metab. 2015 Apr 7;21(4):596-608. doi: 10.1016/j.cmet.2015.03.010. Cell Metab. 2015. PMID: 25863249 Free PMC article.
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Rhodes CJ, Im H, Cao A, Hennigs JK, Wang L, Sa S, Chen PI, Nickel NP, Miyagawa K, Hopper RK, Tojais NF, Li CG, Gu M, Spiekerkoetter E, Xian Z, Chen R, Zhao M, Kaschwich M, Del Rosario PA, Bernstein D, Zamanian RT, Wu JC, Snyder MP, Rabinovitch M. Rhodes CJ, et al. Among authors: rabinovitch m. Am J Respir Crit Care Med. 2015 Aug 1;192(3):356-66. doi: 10.1164/rccm.201408-1528OC. Am J Respir Crit Care Med. 2015. PMID: 26030479 Free PMC article.
473 results