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Page 1
Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes.
Osuna BA, Karambelkar S, Mahendra C, Christie KA, Garcia B, Davidson AR, Kleinstiver BP, Kilcher S, Bondy-Denomy J. Osuna BA, et al. Among authors: kleinstiver bp. Cell Host Microbe. 2020 Jul 8;28(1):31-40.e9. doi: 10.1016/j.chom.2020.04.001. Epub 2020 Apr 22. Cell Host Microbe. 2020. PMID: 32325050 Free PMC article.
Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease.
Choi DE, Shin JW, Zeng S, Hong EP, Jang JH, Loupe JM, Wheeler VC, Stutzman HE, Kleinstiver BP, Lee JM. Choi DE, et al. Among authors: kleinstiver bp. bioRxiv [Preprint]. 2023 Apr 28:2023.04.28.538700. doi: 10.1101/2023.04.28.538700. bioRxiv. 2023. Update in: Elife. 2024 Jun 13;12:RP89782. doi: 10.7554/eLife.89782 PMID: 37162872 Free PMC article. Updated. Preprint.
Discovery of widespread type I and type V CRISPR-Cas inhibitors.
Marino ND, Zhang JY, Borges AL, Sousa AA, Leon LM, Rauch BJ, Walton RT, Berry JD, Joung JK, Kleinstiver BP, Bondy-Denomy J. Marino ND, et al. Among authors: kleinstiver bp. Science. 2018 Oct 12;362(6411):240-242. doi: 10.1126/science.aau5174. Epub 2018 Sep 6. Science. 2018. PMID: 30190308 Free PMC article.
Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer.
Mahendra C, Christie KA, Osuna BA, Pinilla-Redondo R, Kleinstiver BP, Bondy-Denomy J. Mahendra C, et al. Among authors: kleinstiver bp. Nat Microbiol. 2020 Apr;5(4):620-629. doi: 10.1038/s41564-020-0692-2. Epub 2020 Mar 26. Nat Microbiol. 2020. PMID: 32218510 Free PMC article.
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E. Allouche J, et al. Among authors: kleinstiver bp. Cell. 2021 Aug 5;184(16):4268-4283.e20. doi: 10.1016/j.cell.2021.06.022. Epub 2021 Jul 6. Cell. 2021. PMID: 34233163 Free PMC article.
Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
McAlpine CS, Park J, Griciuc A, Kim E, Choi SH, Iwamoto Y, Kiss MG, Christie KA, Vinegoni C, Poller WC, Mindur JE, Chan CT, He S, Janssen H, Wong LP, Downey J, Singh S, Anzai A, Kahles F, Jorfi M, Feruglio PF, Sadreyev RI, Weissleder R, Kleinstiver BP, Nahrendorf M, Tanzi RE, Swirski FK. McAlpine CS, et al. Among authors: kleinstiver bp. Nature. 2021 Jul;595(7869):701-706. doi: 10.1038/s41586-021-03734-6. Epub 2021 Jul 14. Nature. 2021. PMID: 34262178 Free PMC article.
Making the cut with PAMless CRISPR-Cas enzymes.
Christie KA, Kleinstiver BP. Christie KA, et al. Among authors: kleinstiver bp. Trends Genet. 2021 Dec;37(12):1053-1055. doi: 10.1016/j.tig.2021.09.002. Epub 2021 Sep 22. Trends Genet. 2021. PMID: 34563399 Free PMC article.
84 results