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Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Duerr J, Leitz DHW, Szczygiel M, Dvornikov D, Fraumann SG, Kreutz C, Zadora PK, Seyhan Agircan A, Konietzke P, Engelmann TA, Hegermann J, Mulugeta S, Kawabe H, Knudsen L, Ochs M, Rotin D, Muley T, Kreuter M, Herth FJF, Wielpütz MO, Beers MF, Klingmüller U, Mall MA. Duerr J, et al. Among authors: szczygiel m. Nat Commun. 2020 Apr 24;11(1):2012. doi: 10.1038/s41467-020-15743-6. Nat Commun. 2020. PMID: 32332792 Free PMC article.
Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.
Dvornikov D, Schneider MA, Ohse S, Szczygieł M, Titkova I, Rosenblatt M, Muley T, Warth A, Herth FJ, Dienemann H, Thomas M, Timmer J, Schilling M, Busch H, Boerries M, Meister M, Klingmüller U. Dvornikov D, et al. Among authors: szczygiel m. Sci Rep. 2018 Jun 22;8(1):9517. doi: 10.1038/s41598-018-27912-1. Sci Rep. 2018. PMID: 29934580 Free PMC article.
Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.
Marwitz S, Depner S, Dvornikov D, Merkle R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H, Rabe KF, Kugler C, Vollmer E, Reck M, Scheufele S, Kröger M, Ammerpohl O, Siebert R, Goldmann T, Klingmüller U. Marwitz S, et al. Among authors: szczygiel m. Cancer Res. 2016 Jul 1;76(13):3785-801. doi: 10.1158/0008-5472.CAN-15-1326. Epub 2016 May 17. Cancer Res. 2016. PMID: 27197161
Localization of mTORC2 activity inside cells.
Ebner M, Sinkovics B, Szczygieł M, Ribeiro DW, Yudushkin I. Ebner M, et al. Among authors: szczygiel m. J Cell Biol. 2017 Feb;216(2):343-353. doi: 10.1083/jcb.201610060. Epub 2017 Jan 31. J Cell Biol. 2017. PMID: 28143890 Free PMC article.
71 results