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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery.
Abdelnabi R, Kovacikova K, Moesslacher J, Donckers K, Battisti V, Leyssen P, Langer T, Puerstinger G, Quérat G, Li C, Decroly E, Tas A, Marchand A, Chaltin P, Coutard B, van Hemert M, Neyts J, Delang L. Abdelnabi R, et al. Among authors: tas a. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00649-20. doi: 10.1128/AAC.00649-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32340991 Free PMC article.
Transactivation of programmed ribosomal frameshifting by a viral protein.
Li Y, Treffers EE, Napthine S, Tas A, Zhu L, Sun Z, Bell S, Mark BL, van Veelen PA, van Hemert MJ, Firth AE, Brierley I, Snijder EJ, Fang Y. Li Y, et al. Among authors: tas a. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2172-81. doi: 10.1073/pnas.1321930111. Epub 2014 May 13. Proc Natl Acad Sci U S A. 2014. PMID: 24825891 Free PMC article.
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral.
Delang L, Segura Guerrero N, Tas A, Quérat G, Pastorino B, Froeyen M, Dallmeier K, Jochmans D, Herdewijn P, Bello F, Snijder EJ, de Lamballerie X, Martina B, Neyts J, van Hemert MJ, Leyssen P. Delang L, et al. Among authors: tas a. J Antimicrob Chemother. 2014 Oct;69(10):2770-84. doi: 10.1093/jac/dku209. Epub 2014 Jun 20. J Antimicrob Chemother. 2014. PMID: 24951535
The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection.
Delang L, Li C, Tas A, Quérat G, Albulescu IC, De Burghgraeve T, Guerrero NA, Gigante A, Piorkowski G, Decroly E, Jochmans D, Canard B, Snijder EJ, Pérez-Pérez MJ, van Hemert MJ, Coutard B, Leyssen P, Neyts J. Delang L, et al. Among authors: tas a. Sci Rep. 2016 Aug 22;6:31819. doi: 10.1038/srep31819. Sci Rep. 2016. PMID: 27545976 Free PMC article.
352 results