Fu LL - Search Results

1

Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.

Zheng XY, Sun CC, Liu Q, Lu XY, Fu LL, Liang G, Zhang XH, Chen GZ. Zheng XY, et al. Among authors: fu ll. Acta Pharmacol Sin. 2020 Aug;41(8):1093-1101. doi: 10.1038/s41401-020-0410-x. Epub 2020 Apr 27. Acta Pharmacol Sin. 2020. PMID: 32341464 Free PMC article.

2

Synthesis and biological evaluation of novel indole-2-one and 7-aza-2-oxindole derivatives as anti-inflammatory agents.

Chen G, Jiang L, Dong L, Wang Z, Xu F, Ding T, Fu L, Fang Q, Liu Z, Shan X, Liang G. Chen G, et al. Drug Des Devel Ther. 2014 Oct 13;8:1869-92. doi: 10.2147/DDDT.S65997. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25378906 Free PMC article.

3

Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin.

Zhang Y, Jiang X, Peng K, Chen C, Fu L, Wang Z, Feng J, Liu Z, Zhang H, Liang G, Pan Z. Zhang Y, et al. Drug Des Devel Ther. 2014 Nov 4;8:2161-71. doi: 10.2147/DDDT.S69914. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25395833 Free PMC article.

4

Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.

Chen G, Weng Q, Fu L, Wang Z, Yu P, Liu Z, Li X, Zhang H, Liang G. Chen G, et al. Bioorg Med Chem. 2014 Dec 15;22(24):6953-60. doi: 10.1016/j.bmc.2014.10.017. Epub 2014 Oct 29. Bioorg Med Chem. 2014. PMID: 25456085

5

Design, synthesis, and anticancer evaluation of long-chain alkoxylated mono-carbonyl analogues of curcumin.

Weng Q, Fu L, Chen G, Hui J, Song J, Feng J, Shi D, Cai Y, Ji J, Liang G. Weng Q, et al. Eur J Med Chem. 2015 Oct 20;103:44-55. doi: 10.1016/j.ejmech.2015.08.036. Epub 2015 Aug 19. Eur J Med Chem. 2015. PMID: 26318057

6

Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury.

Chen G, Zhang Y, Liu X, Fang Q, Wang Z, Fu L, Liu Z, Wang Y, Zhao Y, Li X, Liang G. Chen G, et al. J Med Chem. 2016 Mar 24;59(6):2436-51. doi: 10.1021/acs.jmedchem.5b01574. Epub 2016 Mar 11. J Med Chem. 2016. PMID: 26937738

7

A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo.

Ge X, Feng Z, Xu T, Wu B, Chen H, Xu F, Fu L, Shan X, Dai Y, Zhang Y, Liang G. Ge X, et al. Drug Des Devel Ther. 2016 Jun 30;10:1947-59. doi: 10.2147/DDDT.S101449. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27390516 Free PMC article.

8

Synthesis and biological evaluation of allylated mono-carbonyl analogues of curcumin (MACs) as anti-cancer agents for cholangiocarcinoma.

Qiu C, Hu Y, Wu K, Yang K, Wang N, Ma Y, Zhu H, Zhang Y, Zhou Y, Chen C, Li S, Fu L, Zhang X, Liu Z. Qiu C, et al. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5971-5976. doi: 10.1016/j.bmcl.2016.10.080. Epub 2016 Oct 28. Bioorg Med Chem Lett. 2016. PMID: 27825763

9

Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.

Chen G, Xiao B, Chen L, Bai B, Zhang Y, Xu Z, Fu L, Liu Z, Li X, Zhao Y, Liang G. Chen G, et al. Eur J Med Chem. 2017 Oct 20;139:726-740. doi: 10.1016/j.ejmech.2017.08.036. Epub 2017 Aug 24. Eur J Med Chem. 2017. PMID: 28858767

10

α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.

Chen G, Liu Y, Goetz R, Fu L, Jayaraman S, Hu MC, Moe OW, Liang G, Li X, Mohammadi M. Chen G, et al. Nature. 2018 Jan 25;553(7689):461-466. doi: 10.1038/nature25451. Epub 2018 Jan 17. Nature. 2018. PMID: 29342138 Free PMC article.

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