Shcherbakova PV - Search Results

1

Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors.

Lee M, Eng G, Barbari SR, Deshpande V, Shcherbakova PV, Gala MK. Lee M, et al. Among authors: shcherbakova pv. Clin Transl Gastroenterol. 2020 Mar;11(3):e00149. doi: 10.14309/ctg.0000000000000149. Clin Transl Gastroenterol. 2020. PMID: 32352724 Free PMC article.

2

A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading.

Kane DP, Shcherbakova PV. Kane DP, et al. Among authors: shcherbakova pv. Cancer Res. 2014 Apr 1;74(7):1895-901. doi: 10.1158/0008-5472.CAN-13-2892. Epub 2014 Feb 13. Cancer Res. 2014. PMID: 24525744 Free PMC article.

3

Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells.

Mertz TM, Baranovskiy AG, Wang J, Tahirov TH, Shcherbakova PV. Mertz TM, et al. Among authors: shcherbakova pv. Oncogene. 2017 Aug;36(31):4427-4433. doi: 10.1038/onc.2017.22. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368425 Free PMC article.

4

Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy.

Barbari SR, Shcherbakova PV. Barbari SR, et al. Among authors: shcherbakova pv. DNA Repair (Amst). 2017 Aug;56:16-25. doi: 10.1016/j.dnarep.2017.06.003. Epub 2017 Jun 9. DNA Repair (Amst). 2017. PMID: 28687338 Free PMC article. Review.

5

Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.

Barbari SR, Kane DP, Moore EA, Shcherbakova PV. Barbari SR, et al. Among authors: shcherbakova pv. G3 (Bethesda). 2018 Mar 2;8(3):1019-1029. doi: 10.1534/g3.118.200042. G3 (Bethesda). 2018. PMID: 29352080 Free PMC article.

6

Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant.

Bulock CR, Xing X, Shcherbakova PV. Bulock CR, et al. Among authors: shcherbakova pv. Nucleic Acids Res. 2020 Sep 18;48(16):9124-9134. doi: 10.1093/nar/gkaa633. Nucleic Acids Res. 2020. PMID: 32756902 Free PMC article.

7

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28.

Stepchenkova EI, Zhuk AS, Cui J, Tarakhovskaya ER, Barbari SR, Shcherbakova PV, Polev DE, Fedorov R, Poliakov E, Rogozin IB, Lada AG, Pavlov YI. Stepchenkova EI, et al. Among authors: shcherbakova pv. Genetics. 2021 Jun 24;218(2):iyab060. doi: 10.1093/genetics/iyab060. Genetics. 2021. PMID: 33844024 Free PMC article.

8

Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels.

Barbari SR, Beach AK, Markgren JG, Parkash V, Moore EA, Johansson E, Shcherbakova PV. Barbari SR, et al. Among authors: shcherbakova pv. Nucleic Acids Res. 2022 Aug 12;50(14):8023-8040. doi: 10.1093/nar/gkac602. Nucleic Acids Res. 2022. PMID: 35822874 Free PMC article.

9

DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors.

Ostroverkhova D, Tyryshkin K, Beach AK, Moore EA, Masoudi-Sobhanzadeh Y, Barbari SR, Rogozin IB, Shaitan KV, Panchenko AR, Shcherbakova PV. Ostroverkhova D, et al. Among authors: shcherbakova pv. Cell Rep. 2024 Jan 23;43(1):113655. doi: 10.1016/j.celrep.2023.113655. Epub 2024 Jan 13. Cell Rep. 2024. PMID: 38219146 Free PMC article.

10

Roles of DNA polymerases in replication, repair, and recombination in eukaryotes.

Pavlov YI, Shcherbakova PV, Rogozin IB. Pavlov YI, et al. Among authors: shcherbakova pv. Int Rev Cytol. 2006;255:41-132. doi: 10.1016/S0074-7696(06)55002-8. Int Rev Cytol. 2006. PMID: 17178465 Review.

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