Han R - Search Results

1

BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity.

Wang P, Xu L, Gao Y, Han R. Wang P, et al. Among authors: han r. Mol Ther. 2020 Jul 8;28(7):1696-1705. doi: 10.1016/j.ymthe.2020.04.009. Epub 2020 Apr 16. Mol Ther. 2020. PMID: 32353322 Free PMC article.

2

Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells.

Xu L, Pallikkuth S, Hou Z, Mignery GA, Robia SL, Han R. Xu L, et al. Among authors: han r. PLoS One. 2011;6(11):e27884. doi: 10.1371/journal.pone.0027884. Epub 2011 Nov 14. PLoS One. 2011. PMID: 22110769 Free PMC article.

3

Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases.

Xu L, Zhao P, Mariano A, Han R. Xu L, et al. Among authors: han r. Mol Ther Nucleic Acids. 2013 Jul 30;2(7):e112. doi: 10.1038/mtna.2013.39. Mol Ther Nucleic Acids. 2013. PMID: 23900226 Free PMC article.

4

Anoctamin 6 regulates C2C12 myoblast proliferation.

Zhao P, Torcaso A, Mariano A, Xu L, Mohsin S, Zhao L, Han R. Zhao P, et al. Among authors: han r. PLoS One. 2014 Mar 24;9(3):e92749. doi: 10.1371/journal.pone.0092749. eCollection 2014. PLoS One. 2014. PMID: 24663380 Free PMC article.

5

Highly efficient genome editing via 2A-coupled co-expression of two TALEN monomers.

Mariano A, Xu L, Han R. Mariano A, et al. Among authors: han r. BMC Res Notes. 2014 Sep 10;7:628. doi: 10.1186/1756-0500-7-628. BMC Res Notes. 2014. PMID: 25204665 Free PMC article.

6

The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.

Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer M, Dowling J, Xu L, Han R, Xu H. Cheng X, et al. Among authors: han r. Nat Med. 2014 Oct;20(10):1187-92. doi: 10.1038/nm.3611. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216637 Free PMC article.

7

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice.

Xu L, Park KH, Zhao L, Xu J, El Refaey M, Gao Y, Zhu H, Ma J, Han R. Xu L, et al. Among authors: han r. Mol Ther. 2016 Mar;24(3):564-9. doi: 10.1038/mt.2015.192. Epub 2015 Oct 9. Mol Ther. 2016. PMID: 26449883 Free PMC article.

8

Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy.

Xu J, El Refaey M, Xu L, Zhao L, Gao Y, Floyd K, Karaze T, Janssen PM, Han R. Xu J, et al. Among authors: han r. Skelet Muscle. 2015 Dec 21;5:43. doi: 10.1186/s13395-015-0069-z. eCollection 2015. Skelet Muscle. 2015. PMID: 26693275 Free PMC article.

9

Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA.

Xu L, Zhao L, Gao Y, Xu J, Han R. Xu L, et al. Among authors: han r. Nucleic Acids Res. 2017 Mar 17;45(5):e28. doi: 10.1093/nar/gkw1048. Nucleic Acids Res. 2017. PMID: 27799472 Free PMC article.

10

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

El Refaey M, Xu L, Gao Y, Canan BD, Adesanya TMA, Warner SC, Akagi K, Symer DE, Mohler PJ, Ma J, Janssen PML, Han R. El Refaey M, et al. Among authors: han r. Circ Res. 2017 Sep 29;121(8):923-929. doi: 10.1161/CIRCRESAHA.117.310996. Epub 2017 Aug 8. Circ Res. 2017. PMID: 28790199 Free PMC article.

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