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Dual SMO/BRAF Inhibition by Flavonolignans from Silybum marianum †.
Diukendjieva A, Zaharieva MM, Mori M, Alov P, Tsakovska I, Pencheva T, Najdenski H, Křen V, Felici C, Bufalieri F, Di Marcotullio L, Botta B, Botta M, Pajeva I. Diukendjieva A, et al. Among authors: botta b, botta m. Antioxidants (Basel). 2020 May 5;9(5):384. doi: 10.3390/antiox9050384. Antioxidants (Basel). 2020. PMID: 32380762 Free PMC article.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: botta b, botta m. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
Targeting GLI factors to inhibit the Hedgehog pathway.
Infante P, Alfonsi R, Botta B, Mori M, Di Marcotullio L. Infante P, et al. Among authors: botta b. Trends Pharmacol Sci. 2015 Aug;36(8):547-58. doi: 10.1016/j.tips.2015.05.006. Epub 2015 Jun 10. Trends Pharmacol Sci. 2015. PMID: 26072120 Review.
One Hundred Faces of Cyclopamine.
Iovine V, Mori M, Calcaterra A, Berardozzi S, Botta B. Iovine V, et al. Among authors: botta b. Curr Pharm Des. 2016;22(12):1658-81. doi: 10.2174/1381612822666160112130157. Curr Pharm Des. 2016. PMID: 26759083 Review.
147 results