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Page 1
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice.
Ballegeer M, Van Looveren K, Timmermans S, Eggermont M, Vandevyver S, Thery F, Dendoncker K, Souffriau J, Vandewalle J, Van Wyngene L, De Rycke R, Takahashi N, Vandenabeele P, Tuckermann J, Reichardt HM, Impens F, Beyaert R, De Bosscher K, Vandenbroucke RE, Libert C. Ballegeer M, et al. Among authors: souffriau j. J Clin Invest. 2018 Aug 1;128(8):3265-3279. doi: 10.1172/JCI96636. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29746256 Free PMC article.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.
Dendoncker K, Timmermans S, Vandewalle J, Eggermont M, Lempiäinen J, Paakinaho V, Van Hamme E, Dewaele S, Vandevyver S, Ballegeer M, Souffriau J, Van Wyngene L, Van Looveren K, Vanderhaeghen T, Beyaert R, De Bosscher K, Palvimo JJ, Van Montagu M, Libert C. Dendoncker K, et al. Among authors: souffriau j. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12942-12951. doi: 10.1073/pnas.1821565116. Epub 2019 Jun 10. Proc Natl Acad Sci U S A. 2019. PMID: 31182584 Free PMC article.
A General Introduction to Glucocorticoid Biology.
Timmermans S, Souffriau J, Libert C. Timmermans S, et al. Among authors: souffriau j. Front Immunol. 2019 Jul 4;10:1545. doi: 10.3389/fimmu.2019.01545. eCollection 2019. Front Immunol. 2019. PMID: 31333672 Free PMC article. Review.
Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis.
Van Wyngene L, Vanderhaeghen T, Timmermans S, Vandewalle J, Van Looveren K, Souffriau J, Wallaeys C, Eggermont M, Ernst S, Van Hamme E, Gonçalves A, Eelen G, Remmerie A, Scott CL, Rombouts C, Vanhaecke L, De Bus L, Decruyenaere J, Carmeliet P, Libert C. Van Wyngene L, et al. Among authors: souffriau j. EMBO Mol Med. 2020 Feb 7;12(2):e11319. doi: 10.15252/emmm.201911319. Epub 2020 Jan 9. EMBO Mol Med. 2020. PMID: 31916705 Free PMC article.
Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium.
Souffriau J, Timmermans S, Vanderhaeghen T, Wallaeys C, Van Looveren K, Aelbrecht L, Dewaele S, Vandewalle J, Goossens E, Verbanck S, Boyen F, Eggermont M, De Commer L, De Rycke R, De Bruyne M, Tito R, Ballegeer M, Vandevyver S, Velho T, Moita LF, Hochepied T, De Bosscher K, Raes J, Van Immerseel F, Beyaert R, Libert C. Souffriau J, et al. EMBO Mol Med. 2020 Oct 7;12(10):e11917. doi: 10.15252/emmm.201911917. Epub 2020 Sep 11. EMBO Mol Med. 2020. PMID: 32914580 Free PMC article.
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation.
Dejager L, Dendoncker K, Eggermont M, Souffriau J, Van Hauwermeiren F, Willart M, Van Wonterghem E, Naessens T, Ballegeer M, Vandevyver S, Hammad H, Lambrecht B, De Bosscher K, Grooten J, Libert C. Dejager L, et al. Among authors: souffriau j. Mucosal Immunol. 2015 Nov;8(6):1212-25. doi: 10.1038/mi.2015.12. Epub 2015 Mar 11. Mucosal Immunol. 2015. PMID: 25760421 Free article.