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A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice.
Valencia-Hernandez AM, Ng WY, Ghazanfari N, Ghilas S, de Menezes MN, Holz LE, Huang C, English K, Naung M, Tan PS, Tullett KM, Steiner TM, Enders MH, Beattie L, Chua YC, Jones CM, Cozijnsen A, Mollard V, Cai Y, Bowen DG, Purcell AW, La Gruta NL, Villadangos JA, de Koning-Ward T, Barry AE, Barchet W, Cockburn IA, McFadden GI, Gras S, Lahoud MH, Bertolino P, Schittenhelm RB, Caminschi I, Heath WR, Fernandez-Ruiz D. Valencia-Hernandez AM, et al. Among authors: purcell aw. Cell Host Microbe. 2020 Jun 10;27(6):950-962.e7. doi: 10.1016/j.chom.2020.04.010. Epub 2020 May 11. Cell Host Microbe. 2020. PMID: 32396839 Free article.
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K. Valkenburg SA, et al. Among authors: purcell aw. PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039. PLoS Pathog. 2010. PMID: 20711359 Free PMC article.
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.
Pang SS, Berry R, Chen Z, Kjer-Nielsen L, Perugini MA, King GF, Wang C, Chew SH, La Gruta NL, Williams NK, Beddoe T, Tiganis T, Cowieson NP, Godfrey DI, Purcell AW, Wilce MC, McCluskey J, Rossjohn J. Pang SS, et al. Among authors: purcell aw. Nature. 2010 Oct 14;467(7317):844-8. doi: 10.1038/nature09448. Nature. 2010. PMID: 20944746
Preemptive priming readily overcomes structure-based mechanisms of virus escape.
Valkenburg SA, Gras S, Guillonneau C, Hatton LA, Bird NA, Twist KA, Halim H, Jackson DC, Purcell AW, Turner SJ, Doherty PC, Rossjohn J, Kedzierska K. Valkenburg SA, et al. Among authors: purcell aw. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5570-5. doi: 10.1073/pnas.1302935110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493558 Free PMC article.
328 results