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Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking.
Sofias AM, Toner YC, Meerwaldt AE, van Leent MMT, Soultanidis G, Elschot M, Gonai H, Grendstad K, Flobak Å, Neckmann U, Wolowczyk C, Fisher EL, Reiner T, Davies CL, Bjørkøy G, Teunissen AJP, Ochando J, Pérez-Medina C, Mulder WJM, Hak S. Sofias AM, et al. ACS Nano. 2020 Jul 28;14(7):7832-7846. doi: 10.1021/acsnano.9b08693. Epub 2020 May 20. ACS Nano. 2020. PMID: 32413260 Free PMC article.
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ. Tang J, et al. Sci Adv. 2015 Apr;1(3):e1400223. doi: 10.1126/sciadv.1400223. Sci Adv. 2015. PMID: 26295063 Free PMC article.
Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy.
Zhao Y, Fay F, Hak S, Manuel Perez-Aguilar J, Sanchez-Gaytan BL, Goode B, Duivenvoorden R, de Lange Davies C, Bjørkøy A, Weinstein H, Fayad ZA, Pérez-Medina C, Mulder WJ. Zhao Y, et al. Nat Commun. 2016 Apr 13;7:11221. doi: 10.1038/ncomms11221. Nat Commun. 2016. PMID: 27071376 Free PMC article.
In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.
Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ. Pérez-Medina C, et al. JACC Cardiovasc Imaging. 2016 Aug;9(8):950-61. doi: 10.1016/j.jcmg.2016.01.020. Epub 2016 May 25. JACC Cardiovasc Imaging. 2016. PMID: 27236528 Free PMC article.
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ. Tang J, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6731-E6740. doi: 10.1073/pnas.1609629113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791119 Free PMC article.
Imaging-guided revival of nanomedicine?
Senders ML, Fayad ZA, Reiner T, Mulder WJ, Pérez-Medina C. Senders ML, et al. Nanomedicine (Lond). 2017 Jan;12(2):89-90. doi: 10.2217/nnm-2016-0365. Epub 2016 Nov 23. Nanomedicine (Lond). 2017. PMID: 27876441 Free PMC article. No abstract available.
56 results