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High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients.
Koçak A, Heselmeyer-Haddad K, Lischka A, Hirsch D, Fiedler D, Hu Y, Doberstein N, Torres I, Chen WD, Gertz EM, Schäffer AA, Freitag-Wolf S, Kirfel J, Auer G, Habermann JK, Ried T. Koçak A, et al. Among authors: hu y. Am J Pathol. 2020 Aug;190(8):1643-1656. doi: 10.1016/j.ajpath.2020.04.015. Epub 2020 May 13. Am J Pathol. 2020. PMID: 32416097 Free PMC article.
Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Padilla-Nash HM, Hathcock K, McNeil NE, Mack D, Hoeppner D, Ravin R, Knutsen T, Yonescu R, Wangsa D, Dorritie K, Barenboim L, Hu Y, Ried T. Padilla-Nash HM, et al. Among authors: hu y. Genes Chromosomes Cancer. 2012 Apr;51(4):353-74. doi: 10.1002/gcc.21921. Epub 2011 Dec 8. Genes Chromosomes Cancer. 2012. PMID: 22161874 Free PMC article.
Molecular patterns in the evolution of serrated lesion of the colorectum.
Gaiser T, Meinhardt S, Hirsch D, Killian JK, Gaedcke J, Jo P, Ponsa I, Miró R, Rüschoff J, Seitz G, Hu Y, Camps J, Ried T. Gaiser T, et al. Among authors: hu y. Int J Cancer. 2013 Apr 15;132(8):1800-10. doi: 10.1002/ijc.27869. Epub 2012 Oct 17. Int J Cancer. 2013. PMID: 23011871 Free PMC article.
Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression.
Heselmeyer-Haddad K, Berroa Garcia LY, Bradley A, Ortiz-Melendez C, Lee WJ, Christensen R, Prindiville SA, Calzone KA, Soballe PW, Hu Y, Chowdhury SA, Schwartz R, Schäffer AA, Ried T. Heselmeyer-Haddad K, et al. Among authors: hu y. Am J Pathol. 2012 Nov;181(5):1807-22. doi: 10.1016/j.ajpath.2012.07.012. Epub 2012 Oct 8. Am J Pathol. 2012. PMID: 23062488 Free PMC article.
Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells.
Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T. Padilla-Nash HM, et al. Among authors: hu y. Carcinogenesis. 2013 Aug;34(8):1929-39. doi: 10.1093/carcin/bgt138. Epub 2013 Apr 25. Carcinogenesis. 2013. PMID: 23619298 Free PMC article.
LGR5 positivity defines stem-like cells in colorectal cancer.
Hirsch D, Barker N, McNeil N, Hu Y, Camps J, McKinnon K, Clevers H, Ried T, Gaiser T. Hirsch D, et al. Among authors: hu y. Carcinogenesis. 2014 Apr;35(4):849-58. doi: 10.1093/carcin/bgt377. Epub 2013 Nov 26. Carcinogenesis. 2014. PMID: 24282287 Free PMC article.
Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis.
Heselmeyer-Haddad KM, Berroa Garcia LY, Bradley A, Hernandez L, Hu Y, Habermann JK, Dumke C, Thorns C, Perner S, Pestova E, Burke C, Chowdhury SA, Schwartz R, Schäffer AA, Paris PL, Ried T. Heselmeyer-Haddad KM, et al. Among authors: hu y. Am J Pathol. 2014 Oct;184(10):2671-86. doi: 10.1016/j.ajpath.2014.06.030. Epub 2014 Aug 14. Am J Pathol. 2014. PMID: 25131421 Free PMC article.
Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.
Emons G, Spitzner M, Reineke S, Möller J, Auslander N, Kramer F, Hu Y, Beissbarth T, Wolff HA, Rave-Fränk M, Heßmann E, Gaedcke J, Ghadimi BM, Johnsen SA, Ried T, Grade M. Emons G, et al. Among authors: hu y. Mol Cancer Res. 2017 Nov;15(11):1481-1490. doi: 10.1158/1541-7786.MCR-17-0205. Epub 2017 Aug 15. Mol Cancer Res. 2017. PMID: 28811361 Free PMC article.
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