Li YC - Search Results

1

Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.

Li YC, Lytle NK, Gammon ST, Wang L, Hayes TK, Sutton MN, Bast RC Jr, Der CJ, Piwnica-Worms D, McCormick F, Wahl GM. Li YC, et al. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12121-12130. doi: 10.1073/pnas.2000848117. Epub 2020 May 18. Proc Natl Acad Sci U S A. 2020. PMID: 32424096 Free PMC article.

2

Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange.

Wong ET, Kolman JL, Li YC, Mesner LD, Hillen W, Berens C, Wahl GM. Wong ET, et al. Among authors: li yc. Nucleic Acids Res. 2005 Oct 4;33(17):e147. doi: 10.1093/nar/gni145. Nucleic Acids Res. 2005. PMID: 16204450 Free PMC article.

3

Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation.

Wang YV, Wade M, Wong E, Li YC, Rodewald LW, Wahl GM. Wang YV, et al. Among authors: li yc. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12365-70. doi: 10.1073/pnas.0701497104. Epub 2007 Jul 17. Proc Natl Acad Sci U S A. 2007. PMID: 17640893 Free PMC article.

4

What a difference a phosphate makes: life or death decided by a single amino acid in MDM2.

Li YC, Wahl GM. Li YC, et al. Cancer Cell. 2012 May 15;21(5):595-596. doi: 10.1016/j.ccr.2012.04.033. Cancer Cell. 2012. PMID: 22624708 Free article.

5

MDM2, MDMX and p53 in oncogenesis and cancer therapy.

Wade M, Li YC, Wahl GM. Wade M, et al. Among authors: li yc. Nat Rev Cancer. 2013 Feb;13(2):83-96. doi: 10.1038/nrc3430. Epub 2013 Jan 10. Nat Rev Cancer. 2013. PMID: 23303139 Free PMC article. Review.

6

Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities.

Green JL, Bauer M, Yum KW, Li YC, Cox ML, Willert K, Wahl GM. Green JL, et al. Among authors: li yc. PLoS One. 2013;8(3):e58395. doi: 10.1371/journal.pone.0058395. Epub 2013 Mar 13. PLoS One. 2013. PMID: 23516471 Free PMC article.

7

A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time.

Li YC, Rodewald LW, Hoppmann C, Wong ET, Lebreton S, Safar P, Patek M, Wang L, Wertman KF, Wahl GM. Li YC, et al. Cell Rep. 2014 Dec 11;9(5):1946-1958. doi: 10.1016/j.celrep.2014.10.058. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25464845 Free PMC article.

8

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters.

Sutton MN, Lu Z, Li YC, Zhou Y, Huang T, Reger AS, Hurwitz AM, Palzkill T, Logsdon C, Liang X, Gray JW, Nan X, Hancock J, Wahl GM, Bast RC Jr. Sutton MN, et al. Among authors: li yc. Cell Rep. 2019 Dec 10;29(11):3448-3459.e6. doi: 10.1016/j.celrep.2019.11.045. Cell Rep. 2019. PMID: 31825828 Free PMC article.

9

Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.

Tang R, Shuldiner EG, Kelly M, Murray CW, Hebert JD, Andrejka L, Tsai MK, Hughes NW, Parker MI, Cai H, Li YC, Wahl GM, Dunbrack RL, Jackson PK, Petrov DA, Winslow MM. Tang R, et al. Among authors: li yc. Nat Cell Biol. 2023 Jan;25(1):159-169. doi: 10.1038/s41556-022-01049-w. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635501 Free PMC article.

10

Multiplex detection of protein-protein interactions using a next generation luciferase reporter.

Verhoef LG, Mattioli M, Ricci F, Li YC, Wade M. Verhoef LG, et al. Among authors: li yc. Biochim Biophys Acta. 2016 Feb;1863(2):284-92. doi: 10.1016/j.bbamcr.2015.11.031. Epub 2015 Nov 28. Biochim Biophys Acta. 2016. PMID: 26646257 Free article.

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