Pardee TS - Search Results

1

The Novel Phospholipid Mimetic KPC34 Is Highly Active Against Acute Myeloid Leukemia with Activated Protein Kinase C.

Alexander PM, Kucera GL, Pladna KM, Pardee TS. Alexander PM, et al. Among authors: pardee ts. Transl Oncol. 2020 Jul;13(7):100780. doi: 10.1016/j.tranon.2020.100780. Epub 2020 May 16. Transl Oncol. 2020. PMID: 32428837 Free PMC article.

2

Improving nucleoside analogs via lipid conjugation: Is fatter any better?

Alexander P, Kucera G, Pardee TS. Alexander P, et al. Among authors: pardee ts. Crit Rev Oncol Hematol. 2016 Apr;100:46-56. doi: 10.1016/j.critrevonc.2016.01.015. Epub 2016 Jan 21. Crit Rev Oncol Hematol. 2016. PMID: 26829896 Free PMC article. Review.

3

The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.

Alexander PM, Caudell DL, Kucera GL, Pladna KM, Pardee TS. Alexander PM, et al. Among authors: pardee ts. PLoS One. 2017 Jun 23;12(6):e0179798. doi: 10.1371/journal.pone.0179798. eCollection 2017. PLoS One. 2017. PMID: 28644853 Free PMC article.

4

A Phase I Study of CPI-613 in Combination with High-Dose Cytarabine and Mitoxantrone for Relapsed or Refractory Acute Myeloid Leukemia.

Pardee TS, Anderson RG, Pladna KM, Isom S, Ghiraldeli LP, Miller LD, Chou JW, Jin G, Zhang W, Ellis LR, Berenzon D, Howard DS, Hurd DD, Manuel M, Dralle S, Lyerly S, Powell BL. Pardee TS, et al. Clin Cancer Res. 2018 May 1;24(9):2060-2073. doi: 10.1158/1078-0432.CCR-17-2282. Epub 2018 Feb 6. Clin Cancer Res. 2018. PMID: 29437791 Free PMC article. Clinical Trial.

5

Inflammatory biomarkers, geriatric assessment, and treatment outcomes in acute myeloid leukemia.

Loh KP, Tooze JA, Nicklas BJ, Kritchevsky SB, Williamson JD, Ellis LR, Powell BL, Pardee TS, Goyal NG, Klepin HD. Loh KP, et al. Among authors: pardee ts. J Geriatr Oncol. 2020 Apr;11(3):410-416. doi: 10.1016/j.jgo.2019.03.014. Epub 2019 Apr 5. J Geriatr Oncol. 2020. PMID: 30962090 Free PMC article.

6

Adenosine Monophosphate Activated Protein Kinase (AMPK) enhances chemotherapy response in Acute Myeloid Leukemia (AML).

Ghiraldeli L, Anderson R, Pladna K, Pardee TS. Ghiraldeli L, et al. Among authors: pardee ts. Cancer Lett. 2022 Jun 1;535:215659. doi: 10.1016/j.canlet.2022.215659. Epub 2022 Mar 20. Cancer Lett. 2022. PMID: 35321842 Free PMC article.

7

Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia.

Anderson R, Miller LD, Isom S, Chou JW, Pladna KM, Schramm NJ, Ellis LR, Howard DS, Bhave RR, Manuel M, Dralle S, Lyerly S, Powell BL, Pardee TS. Anderson R, et al. Among authors: pardee ts. Nat Commun. 2022 Mar 30;13(1):1673. doi: 10.1038/s41467-022-29039-4. Nat Commun. 2022. PMID: 35354808 Free PMC article. Clinical Trial.

8

Pyruvate Dehydrogenase Inhibition Leads to Decreased Glycolysis, Increased Reliance on Gluconeogenesis and Alternative Sources of Acetyl-CoA in Acute Myeloid Leukemia.

Anderson R, Pladna KM, Schramm NJ, Wheeler FB, Kridel S, Pardee TS. Anderson R, et al. Among authors: pardee ts. Cancers (Basel). 2023 Jan 12;15(2):484. doi: 10.3390/cancers15020484. Cancers (Basel). 2023. PMID: 36672433 Free PMC article.

9

Efficacy of the hypomethylating agents as frontline, salvage, or consolidation therapy in adults with acute myeloid leukemia (AML).

Tawfik B, Sliesoraitis S, Lyerly S, Klepin HD, Lawrence J, Isom S, Ellis LR, Manuel M, Dralle S, Berenzon D, Powell BL, Pardee T. Tawfik B, et al. Ann Hematol. 2014 Jan;93(1):47-55. doi: 10.1007/s00277-013-1940-9. Epub 2013 Oct 23. Ann Hematol. 2014. PMID: 24149914 Free PMC article.

10

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells.

Pardee TS, Stadelman K, Jennings-Gee J, Caudell DL, Gmeiner WH. Pardee TS, et al. Oncotarget. 2014 Jun 30;5(12):4170-9. doi: 10.18632/oncotarget.1937. Oncotarget. 2014. PMID: 24961587 Free PMC article.

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