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102 results

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Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model.
Fromont C, Atzori A, Kaur D, Hashmi L, Greco G, Cabanillas A, Nguyen HV, Jones DH, Garzón M, Varela A, Stevenson B, Iacobini GP, Lenoir M, Rajesh S, Box C, Kumar J, Grant P, Novitskaya V, Morgan J, Sorrell FJ, Redondo C, Kramer A, Harris CJ, Leighton B, Vickers SP, Cheetham SC, Kenyon C, Grabowska AM, Overduin M, Berditchevski F, Weston CJ, Knapp S, Fischer PM, Butterworth S. Fromont C, et al. Among authors: grabowska am. J Med Chem. 2020 Jul 9;63(13):6784-6801. doi: 10.1021/acs.jmedchem.9b01803. Epub 2020 Jun 22. J Med Chem. 2020. PMID: 32433887 Free PMC article.
Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells.
Boonsri B, Yacqub-Usman K, Thintharua P, Myint KZ, Sae-Lao T, Collier P, Suriyonplengsaeng C, Larbcharoensub N, Balasubramanian B, Venkatraman S, Egbuniwe IU, Gomez D, Mukherjee A, Kumkate S, Janvilisri T, Zaitoun AM, Kuakpaetoon T, Tohtong R, Grabowska AM, Bates DO, Wongprasert K. Boonsri B, et al. Among authors: grabowska am. Cancer Res Treat. 2021 Apr;53(2):457-470. doi: 10.4143/crt.2020.585. Epub 2020 Oct 7. Cancer Res Treat. 2021. PMID: 33070556 Free PMC article.
3-Dimensional Patient-Derived Lung Cancer Assays Reveal Resistance to Standards-of-Care Promoted by Stromal Cells but Sensitivity to Histone Deacetylase Inhibitors.
Onion D, Argent RH, Reece-Smith AM, Craze ML, Pineda RG, Clarke PA, Ratan HL, Parsons SL, Lobo DN, Duffy JP, Atherton JC, McKenzie AJ, Kumari R, King P, Hall BM, Grabowska AM. Onion D, et al. Among authors: grabowska am. Mol Cancer Ther. 2016 Apr;15(4):753-63. doi: 10.1158/1535-7163.MCT-15-0598. Epub 2016 Feb 12. Mol Cancer Ther. 2016. PMID: 26873730
Individual patient oesophageal cancer 3D models for tailored treatment.
Saunders JH, Onion D, Collier P, Dorrington MS, Argent RH, Clarke PA, Reece-Smith AM, Parsons SL, Grabowska AM. Saunders JH, et al. Among authors: grabowska am. Oncotarget. 2017 Apr 11;8(15):24224-24236. doi: 10.18632/oncotarget.12500. Oncotarget. 2017. PMID: 27736801 Free PMC article.
Effects of Polymer 3D Architecture, Size, and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models.
Pearce AK, Anane-Adjei AB, Cavanagh RJ, Monteiro PF, Bennett TM, Taresco V, Clarke PA, Ritchie AA, Alexander MR, Grabowska AM, Alexander C. Pearce AK, et al. Among authors: grabowska am. Adv Healthc Mater. 2020 Nov;9(22):e2000892. doi: 10.1002/adhm.202000892. Epub 2020 Oct 19. Adv Healthc Mater. 2020. PMID: 33073536
102 results