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Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase.
Cannalire R, Ki Chan KW, Burali MS, Gwee CP, Wang S, Astolfi A, Massari S, Sabatini S, Tabarrini O, Mastrangelo E, Barreca ML, Cecchetti V, Vasudevan SG, Manfroni G. Cannalire R, et al. Among authors: vasudevan sg. ACS Med Chem Lett. 2020 Mar 19;11(5):773-782. doi: 10.1021/acsmedchemlett.9b00619. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435384 Free PMC article.
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.
Yin Z, Chen YL, Kondreddi RR, Chan WL, Wang G, Ng RH, Lim JY, Lee WY, Jeyaraj DA, Niyomrattanakit P, Wen D, Chao A, Glickman JF, Voshol H, Mueller D, Spanka C, Dressler S, Nilar S, Vasudevan SG, Shi PY, Keller TH. Yin Z, et al. Among authors: vasudevan sg. J Med Chem. 2009 Dec 24;52(24):7934-7. doi: 10.1021/jm901044z. J Med Chem. 2009. PMID: 20014868
Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.
Ng IHW, Chan KW, Tan MJA, Gwee CP, Smith KM, Jeffress SJ, Saw WG, Swarbrick CMD, Watanabe S, Jans DA, Grüber G, Forwood JK, Vasudevan SG. Ng IHW, et al. Among authors: vasudevan sg. ACS Infect Dis. 2019 Jun 14;5(6):932-948. doi: 10.1021/acsinfecdis.8b00373. Epub 2019 Mar 19. ACS Infect Dis. 2019. PMID: 30848123
Cell-active carbazole derivatives as inhibitors of the zika virus protease.
Rassias G, Zogali V, Swarbrick CMD, Ki Chan KW, Chan SA, Gwee CP, Wang S, Kaplanai E, Canko A, Kiousis D, Lescar J, Luo D, Matsoukas MT, Vasudevan SG. Rassias G, et al. Among authors: vasudevan sg. Eur J Med Chem. 2019 Oct 15;180:536-545. doi: 10.1016/j.ejmech.2019.07.007. Epub 2019 Jul 17. Eur J Med Chem. 2019. PMID: 31344613
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents.
Felicetti T, Burali MS, Gwee CP, Ki Chan KW, Alonso S, Massari S, Sabatini S, Tabarrini O, Barreca ML, Cecchetti V, Vasudevan SG, Manfroni G. Felicetti T, et al. Among authors: vasudevan sg. Eur J Med Chem. 2021 Jan 15;210:112992. doi: 10.1016/j.ejmech.2020.112992. Epub 2020 Nov 4. Eur J Med Chem. 2021. PMID: 33208235
180 results